与天然存在的野生型酮还原酶相比，本公开提供了具有改善的性质的酮还原酶。
The present disclosure provides ketoreductase enzymes having improved properties as compared to a naturally occurring wild-type ketoreductase enzyme.
在几个番茄茸毛突变体与对应的野生型中，这个基因表达量存在明显差异。
Also significant differences of ShMYB1 expression were detected between several trichome mutants and their wild types.
纯化的重组菊粉酶的其他生物化学性质与海洋季也蒙毕赤酵母中的野生型菊粉酶相一致。
Other biochemical characteristics of the purified recombinant inulinase were the same as those of the native inulinase produced by the marine derived P. guilliermondii strain 1.
方法给一类酪氨酸脱氢酶阳性的神经细胞（一种中枢神经源细胞），又称CAD细胞，引入由DNA编码的野生型和突变型离子通道。
Methods To introduce DNA encoding the wild- type and mutant channel into immortalized tyrosine hydroxylase- positive CNS- derived neurons, CAD cells.
【译】KRAS基因密码子12和13与无病生存的野生型BRAF的II I期结肠癌辅助化疗试验从一个突变(n0147联盟)。
KRAS codon 12 and 13 mutations in relation to disease-free survival in BRAF-wild type stage III colon cancers from an adjuvant chemotherapy trial (N0147 Alliance).
传播的疫苗衍生脊髓灰质炎病毒（cVDPV）在尼日利亚的出现，再次证明尚有不少儿童没有得到保护，使他们免遭脊髓灰质炎病毒的侵袭（无论是野生型还是疫苗衍生型）。
The spread of a circulating vaccine-derived poliovirus in Nigeria reaffirms that not enough children are protected from poliovirus (wild or vaccine-derived).
与水痘相关的一个重要的安全性问题是其对带状疱疹的流行病学的影响—这种影响既见于受接种者，也见于既往曾感染过野生型水痘的个体。
An important safety issue related to the varicella vaccine is the impact on the epidemiology of herpes zoster both in vaccinees as well as in individuals previously infected with wild-type varicella.
作者们发现，缺乏CD 24，这种在免疫细胞和干细胞上表达的膜蛋白的老鼠，产生了比野生型老鼠更强且更致命的炎症反应。
The authors found that mice lacking CD24, a membrane protein expressed by immune and stem cells, developed an inflammatory response that was more powerful and lethal than that in wild-type mice.
当研究者将通过基因改良后的真菌孢子在实验室中释放到蚊子身上后，相对于野生型的真菌，这些改良后的真菌并没有更快的杀死蚊子。
When the researchers sprayed spores of the genetically modified fungus strains onto mosquitoes in the lab, the spores did not kill the insects faster than the normal fungus did.
左图，野生型斑马鱼胚胎已染上红色血细胞，而右图缺乏酶Ago2的变异胚胎则不能产生血细胞。
On left, red blood cells are stained in wild type zebrafish embryos while on the right mutant embryos lacking the enzyme Ago2 fail to produce blood cells.
三个突变异种均显示比野生型具有更高的荧光素酶活性，并且V85I突变异种活性最强。
All three mutants showed higher luciferase activity than that of the wild type, and the V85I mutant showed the highest activity.
当DNA甲基化后，染色体能够顺利植入野生型的丝状支原体。
When the DNA was methylated the chromosome was able to be successfully transplanted into a wild type species of M. capricolum.
结论2002年广东省没有发现由脊灰野生型病毒引起的病例。
Conclusion No polio case caused by wild poliovirus was found of Guangdong province in 2002.
作者报道，有突变患儿和野生型FLT3患儿的完全有效率是相似的。
Complete response rates were similar for children with either mutation and children with wild-type FLT3, the authors report.
上月，达富尔南部地区确定了一例新野生型脊髓灰质炎病毒感染的病例。
The new case of wild poliovirus was confirmed last month in south darfur.
结论同种植物不同居群间亲缘关系的远近与地理来源有关；能够通过聚类分析区分姜黄和川郁金；姜黄属郁金类植物的栽培型和野生型产生了分化。
Clustering approach could make a distinction between Curcuma longa and C. sichuanensis. The differentiation has happened between the wild and cultivated species of Curcuma L.
P16的表达与细胞增殖和凋亡相关，通过导入野生型P 16诱导HCC中细胞凋亡或抑制其增殖，可望提高临床治疗效果。
P16 is related to cell proliferation and apoptosis. Inducing apoptosis and inhabit cell proliferation can improve the clinical therapy effects of HCC.
我们发现CD 8T (CM)和T (EM)在其野生型宿主的排斥反应的移植物中同样有效。
We found that CD8 t (CM) and t (EM) were equally effective at rejecting allografts in wild-type hosts.
就肿瘤的临床及病理特征、染色体拷贝数量改变、突变和表达特征等方面与TCEB1野生型肿瘤进行比较。
Clinical and pathological variables, copy number alterations, mutations, and expression signatures were compared with a cohort of TCEB1 wild-type tumors.
结论野生型和突变型PRPF31基因真核表达载体的构建，为研究PRPF31基因突变引起视网膜色素变性的机制奠定了基础。
Conclusion Construction of the eukaryotic expression vectors of wild type and mutant PRPF31 genes is basic work for research on the mechanisms of retinitis pigmentosa caused by PRPF31 mutation.
结果：与野生型腺病毒相比，重组腺病毒能显著地提高目的基因在四种不同肿瘤细胞中的表达。
Results Fiber-mutant adenovirus vector showed a notably enhanced gene expression in four different tumor cells compared with that of conventional ones.
诱导性的ADH与野生型细菌的本貭性ADH在电泳移动率上没有区别。
The inductive ADH was found to be indistinguishable from its constitutive form in the wild type in regard to electrophoretic mobility.
突变酶w 117y的性质与野生型酶明显不同。
The properties of the mutant enzyme W117Y are very different from wild-type enzyme.
同时还表现出对乙硫氨酸的交叉抗性，其抗性是野生型的6．5倍， 表明该抗性系抗性表达稳定。
The variant cell line also expressed high level of cross resistance to ethionine which was 6.5 fold higher than that of the wild type.
细胞试验表明重组菌对细胞的黏附力和相对侵袭力均有不同程度的降低，而相对侵袭力与野生型菌株具有显著性差异（P<0.05）；
The recombinant strain also had lower adhesiveness(P>0.05)and significantly lower relative invasiveness to the HeLa cells than its wild type strain(P<0.05).
在盐胁迫条件下，野生型和突变体根的生长都受到不同程度的抑制，但对突变体的抑制较为明显。
Under salt stress condition, the root elongation of WT and AtNOSl mutant were both inhibited, but AtNOSl mutant was inhibited much more seriously.
结果表明，燕麦琼脂培养的子实体与野生型子实体无明显区别。
The result shows that no apparent difference was ascertained between field collections and agar-culture fruiting.
统计了不同发育时期的莲座叶叶片数目，发现突变体与野生型的莲座叶叶片数目没有差异。
We calculated the rosette leaf number at different developmental stages, and found that the number of rosette leaves of mutant did not differ significantly from wild type.
统计了不同发育时期的莲座叶叶片数目，发现突变体与野生型的莲座叶叶片数目没有差异。
We calculated the rosette leaf number at different developmental stages, and found that the number of rosette leaves of mutant did not differ significantly from wild type.
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