因此，筛选并鉴定肿瘤B细胞表位对肿瘤疫苗设计具有重要意义。
Selection and identification of B-cell epitopes are important for tumor vaccine designing.
目的探讨利用杂交瘤技术制备肿瘤疫苗的方法，研究肺癌树突状融合细胞的生物学特征。
Objective To explore the established method of tumor vaccine generated by hybrid technique and study the biological characteristics of lung cancer-dendritic fusion cell.
滤泡性B细胞淋巴瘤是一种非霍奇金淋巴瘤，肿瘤疫苗是治疗是根据肿瘤细胞的生物学特殊性。
The cancer vaccines rely on a biological quirk of follicular B-cell lymphoma, which is a type of non-Hodgkin's lymphoma.
结论小鼠脾脏细胞体外诱导培养可生成大量功能成熟的DC，为进一步抗肿瘤疫苗的研究奠定了基础。
Conclusion the functional DC could be induced by amplification cultivation mice spleen derived mononuclear cells in vitro. It would be the foundation of further step to produce antitumor vaccine.
因此，NWBT公司不仅生产出个体化治疗性肿瘤疫苗，还以低廉的成本为患者连续贮存了3年的用药。
So, not only is Northwest BioTherapeutics producing a personalized vaccine to the individual patient, but it's also storing a 3 year stock pile for that patient at low cost.
随着分子生物学及基因工程技术的出现及应用，肿瘤疫苗的研究已成为主动性免疫治疗的重要手段之一。
The research on tumor vaccine has been a key method of tumor active immunotherapy with the development and application of molecular biological and genetic engineering technology.
结论建立稳定表达人MUC1T739小鼠膀胱癌细胞株和t739荷瘤小鼠模型，可用于肿瘤疫苗研究。
Conclusion T739 mouse bladder cancer cell lines and tumor-bear model expressing human MUC1 were successfully established for the development of tumor vaccines targeting MUC1.
现就国内外关于树突状细胞功能研究及基因修饰的肿瘤疫苗临床试验作一综述，以期对未来的研究有所帮助。
This paper overviews the current status of dendritic cell function studies and clinical trials on gene-modified DC vaccine, for the purpose of helping the future research.
免疫治疗包括通过导入抗体或淋巴细胞或者通过肿瘤疫苗免疫接种的方式来控制免疫系统，使其能来识别和清除肿瘤细胞。
Immunotherapy involves the manipulation of the immune system - by introducing an antibody or lymphocytes, or immunization with a tumor vaccine - to recognize and eradicate tumor cells.
然后进行U 251细胞系中肿瘤干细胞的凋亡机制的探讨，从而为脑胶质瘤的防治及肿瘤疫苗的研制提供新的策略和分子靶标。
Then, based on U251 cell lines tumor stem cell apoptosis mechanism will be discussed. Accordingly provide new strategies for the therapy in glioma.
目前已经开发了很多基于树突状细胞的肿瘤疫苗，然而抗肿瘤效果受到实际操作中许多因素的影响，因此研究人员将目光投向新的疫苗制剂。
So, researchers have focused their eyes on some new vaccines. Exosomes are vesicles secrected by different kinds of cells, such as B lymphocytes, tumor cells as well as mast cells.
在使用用癌症疫苗找出更小更隐蔽的肿瘤前，必须先验证它们确实能针对特定癌症并且使快速生长的癌肿缩小。
Before they can seek out these smaller, hidden deposits of tumors, however, cancer vaccines must prove that they can actually target and shrink a cancer's more conspicuous growths.
美国的食品以及药物管理委员会在去年4月份通过了对Provenge的审核，这个癌症疫苗强化了身体免疫系统，使免疫系统会主动攻击肿瘤。
The Food and Drug Administration last April finally approved Provenge, a prostate cancer vaccine that stimulates the body's own immune system to attack tumors.
使用这种方法，他们制成了治疗浸润性黑色素瘤的疫苗康维辛 （Canvaxin），这种疫苗中有20种不同的黑色素瘤肿瘤特异性成分，来把新的疾病识别方法教给人体。
The result was Canvaxin, a vaccine against aggressive melanoma that was loaded up with 20 different tumor-specific components of melanoma, teaching the body new ways to recognize the disease.
《国际肝病》：一些新的免疫药物已经被应用于一些病毒感染性疾病和肿瘤的治疗中，例如，肽类疫苗等。
Hepatology Digest: some new immune agents have been added to the therapy regime of some viral diseases and treatment of tumors, such as peptide vaccines.
目的：探讨负载肿瘤抗原的树突状细胞(DC)疫苗诱导的细胞毒性T淋巴细胞(CTL)的体外杀瘤作用及对荷瘤小鼠的治疗作用。
Objective: to explore the anti-tumor effects of cytotoxic of T-lymphocytes (CTL) induced by dendritic cells (DC) vaccine loaded with tumor antigen.
新城鸡瘟病毒修饰自体肿瘤细胞疫苗能增强患者免疫功能，对放射治疗有协同作用。
Conclusions New castle disease virus-modified autologous tumor vaccine (NDV-ATV) enhances the immunity in cervical carcinoma and synergistically with radiotherapy.
该技术在研究蛋白质之间的相互作用、寻找肿瘤特异性抗原和治疗性靶肽以及在新型诊断试剂和疫苗研制中都有重要用途。
The technique is widely used in exploring protein-protein interactions, finding specific antigens of tumor, cancer targeting therapeutic peptides, new diagnostic agents, and vaccine development.
目的探讨由动员人外周造血祖细胞体外培养扩增获得的树突状细胞(DC)的生物学特性，为临床应用肿瘤树突状细胞疫苗建立制备方法。
Objective to obtain dendritic cells (DCs) from peripheral blood stem cells and hematopoietic precursor cells in vitro, and assess the feasibility of clinical application of tumor vaccine.
黑色素瘤抗独特型抗体疫苗能模拟肿瘤相关抗原，激发机体的抗肿瘤免疫应答，已在许多动物实验和临床试验中得到证实。
It has been demonstrated that anti-idiotypic antibody vaccines against melanoma can mimic tumor-associated antigens and activate anti-tumor immune responses in many animal models and clinical trials.
科学家们研究了一种能够编组人体免疫的植物癌症疫苗，他们说能按患者的特殊肿瘤类型进行适配的裁剪。
The scientists have developed a plant-based cancer vaccine which is capable of marshalling the body's immune response and they say it can be tailored to suit a patient's specific tumour type.
目的：探讨尤文肉瘤细胞总RNA转染的DC疫苗体外诱导特异性抗肿瘤免疫的能力及临床初步应用的效果。
Objective:To observe the ability of DC vaccine transfected with tumor cell total RNA to induce specific antitumor immunity in vitro and the primary clinical application in Ewing sarcoma patients.
其二是MDV在病毒性肿瘤发生和疫苗预防恶性肿瘤研究领域的重要地位，因为MDV是第一个能用实验证明的具有致肿瘤作用的疱疹病毒；
The other is the important position of MDV on tumorigencity and vaccine prevention from malignant neoplasm. Because MDV is the first herpesvirus proved to be oncogenic with experiment.
肿瘤多肽疫苗因其特异性高、化学性质稳定、易于制备、无潜在致癌性等优点，受到愈来愈多的关注。
The peptide vaccines are now drawing more and more attention since they are highly specific, chemically stable, easily prepared and devoid of oncogenic potential.
目 的观察体外构建的榄香烯复合瘤苗抗原-卡介苗 热休克蛋白70复合物（HTA-HSP70BCG）诱导 的树突状细胞疫苗 的抗肿瘤效应。
Objective To investigate antitumor effects induced by dendritic cells (DCs) pulsed with complex of tumor antigen from elemene-combo tumor cell vaccine-heat shock protein 70 of BCG (HTA-HSP70BCG).
本发明还将该重组疟原虫应用于生物治疗和疫苗设计中，尤其是肿瘤的生物治疗和HIV疫苗的设计。
In the invention, the recombinant plasmodium is also applied to biological therapy and vaccine design, in particular to the biological therapy of tumors and the design of HIV vaccine.
本发明还将该重组疟原虫应用于生物治疗和疫苗设计中，尤其是肿瘤的生物治疗和HIV疫苗的设计。
In the invention, the recombinant plasmodium is also applied to biological therapy and vaccine design, in particular to the biological therapy of tumors and the design of HIV vaccine.
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