• 目的建立胆管裸鼠移植模型

    Objective To establish a model of implanted tumor model of human cholangiocarcinoma in nude mice.

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  • 裸鼠移植生长抑制74 5 %。

    The suppression rate of xenograft tumor growth was 74 5%.

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  • 裸鼠移植生长加速

    Remarkable growth acceleration of nude mice tumor transplantation model.

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  • 目的建立稳定肠腺裸鼠移植转移模型

    Objective To establish a stable animal model of metastases of human colon adenocarcinoma implant tumor in nude mice.

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  • 结果血管抑素基因明显抑制卵巢癌裸鼠移植生长

    Results Human angiostatin gene could suppress the growth of transplanted tumor from ovarian neoplasm nude mice obviously.

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  • 裸鼠移植瘤病理组织学结构与原始人体形态相似。

    Pathohistology showed that the structure of the transplantable tumor was similar to that of the original human tumor.

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  • 目的探讨白藜芦醇诱导胃癌细胞裸鼠移植凋亡机制

    AIM: to investigate the molecular mechanism of the apoptosis of implanted tumor of human primary gastric cancer cells in nude mice induced by resveratrol.

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  • 目的探讨人体恶性裸鼠移植瘤试验PCNA表达内在联系。

    Objective To study the relationship between drug sensitive test in nude mouse malignant tumor transplanted from human and PCNA expression.

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  • 结论双歧杆菌诱导大肠癌裸鼠移植细胞凋亡,并能降低它的增殖活性

    CONCLUSION Bifidobacteria could induce apoptosis of nude mouse transplantated tumors of large bowel carcinoma, and decrease the proliferating activity of the tumors.

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  • 方法建立人结肠癌细胞株SW480裸鼠移植模型观察GH移植瘤作用

    Methods The nude mouse model of colonic carcinoma induced with SW480 cell line was established to observe the effects of GH on the transplanted carcinoma.

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  • 目的研究树突状细胞(D C)体外诱导的细胞免疫能否抑制裸鼠移植细胞增殖。

    Objective To study if the immune response in vivo induced by dendritic cells (DC) pulsed with tumor extract can inhibit the growth of implanted tumor in nude mice.

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  • 目的建立稳定、潜伏期短细胞肺癌nci_h4 4 6细胞裸鼠移植瘤模型

    Objective To establish a successful xenotransplantation model of a human small cell lung cancer cell line (NCI_H446) in nude mice.

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  • 方法:观察ysl肝癌BEL- 7402裸鼠移植抑制作用;观察ysl对体外培养。

    Methods: to apply human hepatocarcinoma BEL-7402 tumor transplanted in nude mice to examine the anti-tumor effects of YSL.

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  • 目的研究磁性纳米药物(CDDP -MNP)鼻咽癌裸鼠移植组织靶向性分布

    ObjectiveTo evaluate the targeted distribution of cisplatin loaded magnetic nanoparticles (CDDP-MNP) in tumor tissue of nude mice with nasopharyngeal carcinoma.

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  • 结果:在动物实验中,NCTD明显减少裸鼠移植组织浸润转移结节(P<0.05);

    Results: NCTD significantly reduced tissue invasion around tumor cells and lung metastasis compared with control (P<0.05).

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  • 目的:建立裸鼠h22肝癌移植模型,观察胰岛素是否增强5 -氟脲嘧啶(5 - FU)对裸鼠移植瘤化疗疗效探讨机制

    Objective: to observe whether insulin can enhance the chemotherapeutic response of 5-fluorouracil (5-fu) in transplanted H22 liver cancer in nude mice and to investigate the underlying mechanism.

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  • 结论HCC - 94vHCC - 94新的宫颈癌裸鼠移植株和细胞系,宫颈癌进一步研究提供了理想材料模型

    Conclusion: HCC 94v and HCC 94 could be considered as a new xenografted tumor strain may provide material and model ideal for further investigation of human cervical carcinoma.

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  • 导向治疗结果表明,对荷人肝癌裸鼠移植瘤治疗有效率为100%,与生理盐水组相比具有非常显著的差异(P〈0.01),达到79.38%。

    The targeting therapy on the xenograft in nude mice indicated that the efficiency of the hdsFv-RC-RNase was 100%(P<0.01). The tumor inhibition rate reached 79.38%.

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  • 目的研究血管内皮生长因子受体3 (vascular endothelial growth factor receptor 3, VEGFR - 3)抗体裸鼠移植模型生长抑制作用

    Objective to investigate the inhibitory effect of vascular endothelial growth factor receptor 3 (VEGFR-3) antibody on the transplantation model of human laryngeal squamous carcinoma in nude mice.

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  • 小鼠移植裸鼠异体移植模型研究骆驼(TAH)作用及其协同作用。

    Models of transplanted tumor in mice and human cancer xenograft in nude mice were used to evaluate the antitumor effect and synergism of total alkaloid of Peganum harmala l, (TAH).

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  • 结果松茸多糖明显减少移植体积,减轻移植重量,拮抗移植瘤裸鼠脾脏肝脏指数减少

    Results: Agaricus blazei fungal spores polysaccharide could obviously reduce the volume of the transplanted tumor, decrease its weight, and decrease the index of spleen and liver.

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  • 目的建立成釉细胞裸鼠皮下移植瘤模型

    Objective To establish an subcutaneous xenotransplanted tumor model of human ameloblastoma in nude mice.

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  • 内皮以抑素能抑制裸鼠皮下移植生长P<0.05);

    Endostatin significantly suppressed the growth of the implanted tumor in nude mice (P< 0. 05).

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  • 结论本研究所建立裸鼠移植肝细胞肝癌模型率高移植生长良好,便于MRI观察一种适合分子影像学研究的动物模型。

    Conclusion The nude mouse model with FHCC, with ideal implantation and tumor growth rate, was convenient for MRI observation and suitable for molecular imaging research of human HCC.

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  • 裸鼠皮下移植生长受抑制

    Growth of the subcutaneous transplanted tumors in the nude mice decreased.

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  • 目的:初步探讨强度聚焦超声裸鼠卵巢癌皮下移植治疗前后超声磁共振变化

    Objective: To study changes of ultrasound and magnetic resonance image of high intensity focused ultrasound (HIFU) in the treatment of subcutaneous ovary carcinoma of nude mice.

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  • 同时制备裸鼠u251细胞移植模型注射重组腺病毒观察生长情况。

    The recombinant viruses were injected into the xenograft tumors of U251 cells in nude mice, then the tumor growth was observed.

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  • 结果成功建立了裸鼠皮下移植模型

    Results The subcutaneous tumor model in nude mice was successfully established.

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  • 结论TNP- 470对u - 251胶质母细胞细胞裸鼠皮下移植瘤生长具有抑制作用而无明显毒副作用。

    Conclusion TNP-470 could significantly inhibit the growth of human glioblastoma U-251 xenografts in the nude mice without evident side effect.

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  • 目的探讨TNP- 470对u - 251胶质母细胞细胞裸鼠皮下移植瘤生长影响。

    Objective to investigate the effect of TNP-470 on growth of subcutaneously implanted human glioblastoma U-251 xenografts in nude mice.

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