近四十岁时，由于事业上的挫折，他几乎为失意所毁。

Nearly forty years old, he almost been crashed because of frustration of business.

youdao

近四十岁时，由于事业上的挫折，他几乎为失意所毁。

Nearly forty years old, he almost been crashed because of frustration of business.

youdao