目的研究预注法及限时法能否缩短顺阿曲库铵的起效时间。
Objective To study the effect of the priming principle and the timing principle on the onset time of cisatracurium.
结论肝功能严重障碍患者顺阿曲库铵最大阻滞程度下降，起效时间延长，诱导时应增加给药剂量。
ConclusionMaximum blockade effect of cisatracurium besylate in patients with severe liver dysfunction was lower and onset time was longer. Dosage of cisatracurium should be increased.
结论肝功能严重障碍患者顺阿曲库铵最大阻滞程度下降，起效时间延长，诱导时应增加给药剂量。
ConclusionMaximum blockade effect of cisatracurium besylate in patients with severe liver dysfunction was lower and onset time was longer. Dosage of cisatracurium should be increased.
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