Objective: to determine the toxic effect 0f aciclovir gel on skin.
目的:观察阿昔洛韦凝胶对动物皮肤的毒性作用。
Conclusion: Topical use of aciclovir gel on the animal skin is safe.
结论:阿昔洛韦凝胶皮肤局部用药对实验动物较为安全。
OBJECTIVE to establish a method to determine the dissolution of Aciclovir tablet.
目的建立阿昔洛韦片的溶出度检查方法。
OBJECTIVE: Preparation of compound aciclovir gel and establish a method of quality control by HPLC.
目的:制备复方阿昔洛韦凝胶并建立其质量控制方法。
CONCLUSIONS: There is incompatibility between gatifloxacin for injection and aciclovir for injection.
结论注射用加替沙星与注射用阿昔洛韦存在配伍禁忌。
Objective To prepare aciclovir sustained-release pellets and investigate the drug release mechanism in vitro.
目的制备阿昔洛韦缓释微丸,并对其体外释药情况进行研究。
Conclusion The test for bacterial endotoxins of aciclovir for injection may be conducted for its quality control.
可用细菌内毒素检查法代替家兔热原检查法来控制该制剂热原。
RESULTS: the releasing curve of the aciclovir eye gel in vitro was in line with the first-order drug releasing equation.
结果:阿昔洛韦眼用凝胶体外释放曲线符合一级释药方程。
OBJECTIVE To study the preparation of aciclovir loaded albumin microspheres (ACV BSA MS) and evaluate its morphology, drug loading and release in vitro.
目的优化阿昔洛韦白蛋白微球的制备工艺,并对其形态学性质、载药量、体外释药进行考察。
Results: no irritation of aciclovir gel on the integral or damaged skin of rabbit was observed. Sensitization effect on the skin of guinea pig was not found.
结果:阿昔洛韦凝胶对家兔完整皮肤和破损皮肤均无刺激性,对豚鼠完整皮肤无致敏性。
Objective To observe the effect of immunity condition and clinical manifestations of children with recurrent oral-ulcer(ROU)treated with aciclovir(ACV) and a-polyresistin.
目的观察阿昔洛韦(ACV)联合多抗甲素全身治疗效果,以及对复发性口腔溃疡(ROU)患儿免疫状态的影响。
OBJECTIVES: To study the dissolution amounts of aciclovir (ACV) from differently based preparations and provide the evidence for the development of new preparation of ACV.
目的:研究不同基质阿昔洛韦(ACV)外用制剂的药物溶出度,为开发新的ACV外用制剂提供依据。
Objective To study the effect of different solvent systems on in vitro penetration rate of aciclovir gel enhanced by Azone for optimizing the formulation of aciclovir gel.
目的研究阿昔洛韦凝胶中的不同溶剂系统对主药体外透皮速率及对氮酮促渗作用的影响,为优化阿昔洛韦凝胶处方提供实验依据。
METHODS The aciclovir eye ointment was used as control group, and the gel as test group, the drug action on treatment of experimental rabbits herpes simplex keratitis (HSK) was compared.
方法:选用市售阿昔洛韦眼膏作为对照组,阿昔洛韦眼用凝胶剂为实验组,比较两者治疗实验性家兔单纯疱疹性角膜炎的药效差异。
METHODS The aciclovir eye ointment was used as control group, and the gel as test group, the drug action on treatment of experimental rabbits herpes simplex keratitis (HSK) was compared.
方法:选用市售阿昔洛韦眼膏作为对照组,阿昔洛韦眼用凝胶剂为实验组,比较两者治疗实验性家兔单纯疱疹性角膜炎的药效差异。
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