OBJECTIVE to prepare the acyclovir ACV palmitate liposome gel in order to raise ACV concentration in the skin and enhance the topical bioavailability of ACV.
目的为了增加阿昔洛韦在皮肤中的滞留量，提高局部生物利用度，制备了阿昔洛韦棕榈酸酯脂质体凝胶剂。
Methods:Cytotoxity of acyclovir(ACV)on Vero cell and antiviral activity of ACV on herpes simplex virus type 1(HSV-1)in vitro were detected using two methods.
方法：在体外用两种方法检测阿昔洛韦（ACV）对细胞毒性作用和抗单纯疱疹病毒1型（HSV-1）的作用。
Objective to set up a method to determine the concentration of Acyclovir (ACV) in Muan eye ointment with HPLC for the study of the ointment pharmacokinetics in rabbit aqueous humor.
目的建立HPLC法测定目安眼膏在家兔房水内阿昔洛韦(ACV)含量的方法，为目安眼膏在兔眼内转运动力学研究提供定量方法。
Objective to set up a method to determine the concentration of Acyclovir (ACV) in Muan eye ointment with HPLC for the study of the ointment pharmacokinetics in rabbit aqueous humor.
目的建立HPLC法测定目安眼膏在家兔房水内阿昔洛韦(ACV)含量的方法，为目安眼膏在兔眼内转运动力学研究提供定量方法。
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