ATM kinase regulates a number of proteins involved in cell cycle checkpoint control, apoptosis, and DNA repair.
AT M激酶调节许多蛋白，涉及细胞周期检验点的控制、细胞凋亡和DNA修复。
To maintain genomic integrity, cells have evolved complex surveillance mechanisms termed cell cycle checkpoint.
为确保遗传准确性，细胞形成了复杂的细胞周期监督机制，即细胞周期检验点。
Several factors, such as defects in chromosome segregation and DNA damage response, failure of cell cycle checkpoint, telomere dysfunction, may cause chromosomal instability.
多种细胞机制功能障碍将导致染色体不稳定性，包括染色体分离、DNA损伤反应、细胞周期检查点、端粒功能等。
Highly conserved DNA-repair and cell-cycle checkpoint pathways allow cells to deal with both endogenous and exogenous sources of DNA damage.
高度保守的DNA修复和细胞周期检查点通路使得细胞能够应付各种内源性或外源性因素引起的DNA损伤。
Highly conserved DNA-repair and cell-cycle checkpoint pathways allow cells to deal with both endogenous and exogenous sources of DNA damage.
高度保守的DNA修复和细胞周期检查点通路使得细胞能够应付各种内源性或外源性因素引起的DNA损伤。
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