• Oncogene-Induced Cell Senescence ― Halting on the Road to Ca…

    关于癌基因诱导细胞衰老和癌症发生的关系…

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  • Telomere, which defines the ends of chromosome, has close relationship with cell senescence and apoptosis.

    细胞的衰老与死亡和细胞核的染色体末端——端粒有密切的关系。

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  • We observed the influence of aging or caloric restriction (cr) on pancreatic beta cell senescence and its insulin secretion.

    本研究旨在研究增龄或限制能量摄入(CR)对胰岛细胞衰老及胰岛素分泌的影响。

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  • The main function of telomerase is for the replication of telomere DNA, which is closely related with tumor and cell senescence.

    端粒酶的主要功能是复制端粒末端dna,维持端粒长度。端粒酶活性调节与肿瘤发生和细胞衰老有着密切关系。

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  • Summary of Background Data. Cell senescence has been recognized as a potential factor playing a role age-related disc degeneration.

    细胞衰老被认为是在年龄相关椎间盘退变中起作用的一个潜在因子。

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  • AIM: to clone and analyze the mouse LASS1 gene promoter, so as to lay a foundation for the further research of the transcriptional regulation of LAG1 gene in cell senescence.

    目的:克隆并应用计算机分析小鼠lass1基因启动子,为进一步研究在细胞衰老过程中LAG1基因的转录调控奠定基础。

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  • Telomere and telomerase are the focus of modern biological study. There are close relationships among telomere loss and cell ageing, activation of telomerase, cell senescence and immortalization.

    端粒和端粒酶是现代生物学研究的热点,端粒的缺失与细胞的衰老,端粒酶的活性与细胞的老化及癌化均有密切的关系。

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  • Ceramide is a lipid molecule naturally present in the cell's plasma membrane and controls cell functions, including cell aging, or senescence.

    神经酰胺是一种脂质分子,通常存在于在细胞的胞膜上,并且能够调节细胞的功能:包括细胞老化或衰老。

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  • Expression of an oncogene in a primary cell can, paradoxically, block proliferation by inducing senescence or apoptosis through pathways that remain to be elucidated.

    初始细胞的癌基因的表达往往会通过诱导细胞凋亡、衰老来阻止细胞的增值的,而其实现上述功能的具体途径仍有待澄清。

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  • Instead the cells underwent cell cycle arrest with features of senescence.

    代之以衰老为特征的细胞周期阻滞的表现。

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  • AIM: to investigate the inductive effects of D-galactose, which can induce cell aging of fibroblasts and neurons, on the modeling senescence of cardiac myocytes in rats.

    目的:观察可诱导成纤维细胞、神经元细胞衰老的D -半乳糖对心肌细胞拟衰老的诱导作用。

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  • Objective: To explore the expressive mechanism of induced HSP70 and it' s effect on the senescence of MRC-5 cell in the heat shock condition.

    目的:探讨在热休克条件下,人胚肺二倍体细胞MRC-5株诱导型热休克蛋白70(HSP70)在细胞水平的表达机制,以及对MRC-5细胞衰老的影响。

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  • Telomerase is closely related with cell growth, proliferation, senescence and carcinogenesis.

    端粒酶与细胞生长、繁殖、衰老及肿瘤的发生密切相关。

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  • Senescence may be defined as the deteriorative events which precede the death of a mature cell.

    衰老是成熟细胞死亡之前的败坏过程。

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  • This research reveals that SPATA4 gene can inhibit cellular senescence and apoptosis as well as promote the progression of cell cycle and cell proliferation;

    本研究发现SPATA4基因能够抑制细胞衰老和细胞凋亡、促进细胞周期的推进与细胞增殖;

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  • The expression of cloned gene in HeLa cells did not induce the cell apoptosis or senescence.

    钙调素基因在真核细胞中表达没有引起肿瘤细胞的凋亡和衰老。

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  • When the Arabidopsis gene MAX2/ORE9 is disrupted, leaf senescence or cell death in response to the above stimuli is delayed.

    当拟南芥MAX2/ORE9基因丧失功能时,黑暗诱导的植物叶片衰老和过氧化氢诱导的植物叶片细胞死亡将被延缓。

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  • Senescence and apoptosis are two important physiological processes which are always study most in cell biology field.

    衰老和凋亡是细胞的两个重要生理过程,一直以来都是细胞生物学领域研究的热点。

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  • The expression in HeLa cells could induce the cell apoptosis instead of senescence.

    钙调素基因在真核细胞中表达没有引起肿瘤细胞的凋亡和衰老。

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  • The expression in HeLa cells could induce the cell apoptosis instead of senescence.

    钙调素基因在真核细胞中表达没有引起肿瘤细胞的凋亡和衰老。

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