With the thorough research of tumor mechanism, drugs acting on cell signal transduction pathway began to attract attention of researchers as an important target for anticancer drug development.
随着对肿瘤发生机制研究的深入,作用于细胞信号转导通路的药物开始引起研究者的关注,成为抗肿瘤药物研发的重要靶点之一。
In hyperosmotic stress, the HOG-MAPK pathway regulates the signal transduction and expression of numerous genes for cell survival.
该途径在高渗应激环境下控制信号转导和基因表达,是细胞生存所必需的。
Objective To evaluate the inhibiting effect of selective and non-selective cyclo-oxygenase-2(COX-2) inhibitor on growth of colon cancer cell lines in vitro and its signal transduction pathway.
目的探讨选择性及非选择性环氧合酶-2抑制剂(COX-2)对体外培养的结肠癌细胞生长的影响及其作用的信号传导通路。
Gefitinib is protein tyrosine kinase inhibitor of a selective EGFR, can block the signal transduction pathway of tyrosine protein kinase, and then promote tumor cell apoptosis.
吉非替尼为一种选择性的EGFR一蛋白酪氨酸激酶抑制剂,能阻断酪氨酸蛋白激酶信号传导通路,从而促进肿瘤细胞凋亡。
This review briefly focused on the new targets and agents from the following four aspects: signal transduction pathway, cell survival pathway, gene therapy, and angiogenesis.
文章从细胞信号传导通路、细胞生存途径、基因治疗及血管生成四方面简要介绍这些新靶点和已经或正在研发的新药物。
Suppressors of cytokine signaling (SOCS) associates with receptor-mediated signal transduction pathway, which can regulate cell proliferation, growth, differentiation and inflammation et al.
细胞因子信号转导抑制蛋白(SOCS)通过与受体介导的信号转导,调节细胞增殖、生长、分化及炎症发生等。
CONCLUSION: MAPK signal transduction pathway participates the proliferation inhibition of cantharidin on A549 cell.
结论:MAPK信号传导途径参与了斑蝥素对人肺癌a5 49细胞的增殖抑制作用。
This article reviews effects of UA on cancer cell proliferation signal transduction pathway and anti-vascular disease in order to provide some new ideas on the development of UA.
本文就UA对肿瘤细胞增殖信号通路的影响和抗心血管疾病作用研究进展方面进行综述,以期为UA的开发提供新思路。
To understand further the molecular mechanism of its function, human neuroblastoma SK N SH cell line was chosen as a model to study its signal transduction pathway.
为了进一步阐明其作用的分子机制,以SKNSH成神经瘤细胞(SK细胞)为模型进行了研究。
Furthermore, through cell surface or nucleus receptors and signal transduction pathway, cell can absorb various stimulation, at the same time, react according to the different microenvironment.
这些复杂的细胞结构通过细胞表面与细胞核内的受体、信号转导途径等实现对刺激信号的吸收并根据不同的微环境做出相应的应答。
Objective To discuss the relationship between estradiol and the mitogenic activated protein kinase signal transduction pathway and the expression of the MAPK in the MCF-7 breast cancer cell-line.
目的探讨雌二醇与有丝分裂素激活蛋白激酶(MAPK)信号通路的关系以及MAPK在乳腺癌细胞系中的表达情况。
The most important of these pathways are the signal transduction pathway, the cell-cycle control pathway, the apoptotic pathway, and the angiogenesis-metastasis route.
其中最重要的包括信号转导、细胞周期调控,凋亡以及血管生成-肿瘤转移。
The most important of these pathways are the signal transduction pathway, the cell-cycle control pathway, the apoptotic pathway, and the angiogenesis-metastasis route.
其中最重要的包括信号转导、细胞周期调控,凋亡以及血管生成-肿瘤转移。
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