• With the thorough research of tumor mechanism, drugs acting on cell signal transduction pathway began to attract attention of researchers as an important target for anticancer drug development.

    随着肿瘤发生机制研究深入,作用细胞信号转导通路药物开始引起研究者关注,成为抗肿瘤药物研发的重要靶点之一

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  • In hyperosmotic stress, the HOG-MAPK pathway regulates the signal transduction and expression of numerous genes for cell survival.

    途径高渗应激环境下控制信号转导基因表达,是细胞生存所必需

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  • Objective To evaluate the inhibiting effect of selective and non-selective cyclo-oxygenase-2(COX-2) inhibitor on growth of colon cancer cell lines in vitro and its signal transduction pathway.

    目的探讨选择性非选择性环氧合酶-2抑制剂COX-2)对体外培养结肠癌细胞生长影响及其作用的信号传导通路

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  • Gefitinib is protein tyrosine kinase inhibitor of a selective EGFR, can block the signal transduction pathway of tyrosine protein kinase, and then promote tumor cell apoptosis.

    非替尼为选择性EGFR一蛋白酪氨酸激酶抑制剂阻断酪氨酸蛋白激酶信号传导通路从而促进肿瘤细胞凋亡。

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  • This review briefly focused on the new targets and agents from the following four aspects: signal transduction pathway, cell survival pathway, gene therapy, and angiogenesis.

    文章细胞信号传导通路细胞生存途径基因治疗血管生成方面简要介绍这些靶点已经或正在研发的新药物

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  • Suppressors of cytokine signaling (SOCS) associates with receptor-mediated signal transduction pathway, which can regulate cell proliferation, growth, differentiation and inflammation et al.

    细胞因子信号转导抑制蛋白(SOCS)通过受体介导的信号转导调节细胞增殖生长分化炎症发生

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  • CONCLUSION: MAPK signal transduction pathway participates the proliferation inhibition of cantharidin on A549 cell.

    结论MAPK信号传导途径参与斑蝥素人肺癌a5 49细胞增殖抑制作用

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  • This article reviews effects of UA on cancer cell proliferation signal transduction pathway and anti-vascular disease in order to provide some new ideas on the development of UA.

    本文UA肿瘤细胞增殖信号通路影响抗心血管疾病作用研究进展方面进行综述以期为UA的开发提供思路

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  • To understand further the molecular mechanism of its function, human neuroblastoma SK N SH cell line was chosen as a model to study its signal transduction pathway.

    为了进一步阐明作用分子机制,以SKNSH成神经细胞(SK细胞)模型进行研究

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  • Furthermore, through cell surface or nucleus receptors and signal transduction pathway, cell can absorb various stimulation, at the same time, react according to the different microenvironment.

    这些复杂的细胞结构通过细胞表面细胞核内受体、信号转导途径等实现对刺激信号吸收根据不同的微环境做出相应应答

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  • Objective To discuss the relationship between estradiol and the mitogenic activated protein kinase signal transduction pathway and the expression of the MAPK in the MCF-7 breast cancer cell-line.

    目的探讨雌二醇分裂素激活蛋白激酶(MAPK)信号通路关系以及MAPK乳腺癌细胞系中的表达情况。

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  • The most important of these pathways are the signal transduction pathway, the cell-cycle control pathway, the apoptotic pathway, and the angiogenesis-metastasis route.

    其中重要包括信号转导细胞周期调控,凋亡以及血管生成-肿瘤转移。

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  • The most important of these pathways are the signal transduction pathway, the cell-cycle control pathway, the apoptotic pathway, and the angiogenesis-metastasis route.

    其中重要包括信号转导细胞周期调控,凋亡以及血管生成-肿瘤转移。

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