Results: Drug release rate of the tablets did not change with the change of medium.
结果:渗透泵的释药不随释药环境的改变而改变。
Through the adjustment on the two molecular parameters, CS-NP with various mean size and drug release rate could be obtained.
具有较大粒径的去甲斑蝥素壳聚糖纳米粒能够实现肝脏靶向,提高药物疗效,降低全身毒副作用。
The effects of different drug loadings on the drug release rate were simulated and compared with other data to validate this model.
模拟不同载药量对药物释放速率的影响并与其它数据进行比较,以此来验证此模型。
Factors influencing the drug release rate, including drug loading, species and amount of additives, hardness, particle size were studied.
考察载药量、填充剂种类和用量、硬度、辅料粒径等因素对药物释放的影响。
The drug release rate and concentration was related with the concentration of MTX in compound but not with the thickness and shape of CPC.
MTX释放浓度及速度与MTX在骨水泥中的包埋量有关,与骨水泥的厚度及形状无关。
Drug release rate was significantly influenced by release area, stirring speed of peddles and the sorts of dispersion mediums respectively.
释放面积,桨的搅拌速度及释放介质均影响脂质体凝胶的溶蚀及药物的释放。
Polymers play a crucial role in controlling drug release rate, enhancing drug solubility and uptake, and limiting drug degradation and toxicity.
聚合物在控制药释放率,提升药溶解度和举起,并且限制药堕落和毒性中起决定性作用。
While NVP was incorporated into polymer drug, it had little effect on release in acid condition, but drug release rate in base condition increased markedly.
同时,共聚物中亲水组分—NVP的引入,对酸性条件下的释放影响不大,但明显加快了药物在碱性条件下释放。
Membrane materials with special functional features or combination of different types of materials can also be used to regulate the drug release rate of the pellets.
还可利用衣膜材料不同的功能特性或不同类型材料的组合调节药物的释放速率。
Microsphere size, which has a significant effect on drug release rate, can potentially be varied to design a controlled drug delivery system with desired release profile.
微球大小对药物释放率有很重要的影响,人们认为可以改变其大小以建立一个药物释放符合需要能够控制药物释放的体系。
The swelling ratio and drug release rate of citrate cross-linked chitosan in SGF was much more quick than that in SIF, so these film may be used as a drug carrier in the stomach.
柠檬酸根交联壳聚糖膜在SGF中的溶胀以及药物的释放速率比在SIF大得多,这表明这些膜有望作为胃部给药的控释载体。
We show from in vitro release experiments that microsphere size has a significant effect on drug release rate. The initial release rate decreased with an increase in microsphere size.
从体外释放试验中可知微球大小对药物释放率有很大的作用。药物开始释放率与微球大小负相关。
At the same time, the effects of the coating solvent, DBP, PEG-400, coating level, spray rate, air temperature and pan speed on the drug release character are investigated.
同时,考察了包衣溶剂、DBP、PEG- 400、衣膜增重、喷雾速度、包衣温度和包衣锅转速对药物释放的影响。
CONCLUSIONS the rate of drug release is proportional to the ionic strength.
结论:释药速率与离子强度之间存在较好的线性负相关关系。
Electron microscope scanning of the drug coating film of before and after drug release indicates that adding hydrophilic shaping agent could improve the penetration rate of the coating film.
对释药前后的包衣膜进行电镜扫描,结果表明包衣膜中加入亲水性增塑剂可改善包衣膜的通透性。
Cell inhibition rate (IR) was calculated after C6 glioma cells were cultured in the controlled drug release system for testifying tumor-killing effect of the controlled drug release system.
利用C6胶质瘤细胞在药物缓释体中培养后计算细胞抑制率(IR)验证药物缓释体的缓释杀瘤效果。
RESULTS The influx of water that passed the osmotic pump tablet was greatly less than the drug dissolution rate from tablet core and the bergenin release rate.
结果水透膜的速率远小于片芯中药物的溶出速率及岩白菜素渗透泵片的释药速率;
The invention improves the carrier and packing rate of nanometer particles, and controls the instant release condition of hydrophobic drug.
提 高了纳米粒子的载药量及包封率,控制了疏水性药物的突释现象。
The drug loading rate, encapsulation efficiency, particle distribution and in vitro release of Lac-NCTD from liposomes were investigated, respectively.
考察了药物与磷脂的复合率,磷脂复合物脂质体的包封率,粒径大小和分布,以及体外释药特性。
OBJECTIVE the effect of different diluents on the release rate of insoluble drug from HPMC hydrogel matrix was investigated.
目的探讨稀释剂对难溶性药物的hpmc骨架片释药的影响。
RESULTS Using the release rate of Rhein from film as an evaluation index, the in vitro drug releases were well.
结果以膜剂中大黄酸的释放度为评价指标,膜剂体外缓释效果良好。
HA with a specific targeting property could increase the bioavailability of paclitaxel and control the release rate of the drug.
既利用透明质酸对癌细胞的靶向性,提高了紫杉醇的生物利用度,又达到了药物缓释的效果。
The drug-loading rate of this chitosan-levofloxacin sustained-release microsphere is 43.88%. Its in vitro dissolubility is good.
该方法制备的左氧氟沙星-壳聚糖缓释微球载药量为43.88%,体外累积释放度的线形关系良好。
Abstract: Response surface methodology was applied to optimize the drug loading rate of persimmon leaf total flavonoids sustained release pellets.
摘要:本文研究了响应面法优化柿叶总黄酮缓释微丸的载药量。
Hang-'em-high Texas, by financing drug-treatment and mental-health services and improving post-release supervision, has dramatically slowed the rate of growth of its prison population.
通过资助戒除毒瘾项目,心理健康服务以及提高囚犯出狱后的监督,动辄“大刑伺候”的德克萨斯州极大地减缓了囚犯人口的增长速度。
Hang-'em-high Texas, by financing drug-treatment and mental-health services and improving post-release supervision, has dramatically slowed the rate of growth of its prison population.
通过资助戒除毒瘾项目,心理健康服务以及提高囚犯出狱后的监督,动辄“大刑伺候”的德克萨斯州极大地减缓了囚犯人口的增长速度。
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