The objective is to explore the role of efflux pump in drug resistance to fluoroquinolones in Stenotrophomonas maltophilia.
目的是探讨外排泵在嗜麦芽窄食单胞菌中对氟喹诺酮类药物的耐药性中的作用。
Efflux pump inhibitors may partly reduce the resistance.
泵抑制剂可部分逆转这种耐药性。
Objective:To explore the role of efflux pump in drug resistance to fluoroquinolones in Stenotrophomonas maltophilia.
目的：探讨主动外排泵在嗜麦芽寡养单胞菌对氟喹诺酮类药物耐药中的作用。
One might anticipate that calcium efflux, like that of sodium, is mediated by an ATP-dependent pump.
人们可以推测，钙的外流象钠一样是由atp—依赖的泵来完成。
MIC was decreased by inhibitory of efflux pump in 70% resistant bacteria.
应用外排泵抑制剂利血平后，70%诱导耐药菌mic有明显下降。
The resistance to quinolones in clinical isolates of Pseudomonas aeruginosa is due to the mutations of two types of topoisomerase plus efflux pump.
结论铜绿假单胞菌的耐药性日趋严重，两类拓扑异构酶基因突变和泵出机制形成了铜绿假单胞菌对喹诺铜类药物耐药的主要机制。
The resistance to quinolones in clinical isolates of Pseudomonas aeruginosa is due to the mutations of two types of topoisomerase plus efflux pump.
结论铜绿假单胞菌的耐药性日趋严重，两类拓扑异构酶基因突变和泵出机制形成了铜绿假单胞菌对喹诺铜类药物耐药的主要机制。
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