Fatty acid synthase (FAS) catalyzes the synthesis of long-chain fatty acids from acetyl-CoA and malonyl-CoA.
脂肪酸合成酶(FAS)催化乙酰辅酶a和丙二酰辅酶A合成长链脂肪酸。
Fatty acid synthase converts those sugars to fatty acids in the liver, where they play important roles in energy metabolism.
在肝脏里,脂肪酸合成酶可将这些糖转化为脂肪酸,在那里脂肪和糖将充当起能量代谢中的重要角色。
Animals can't survive without fatty acid synthase, so mice in this study were able to make the substance in most of their tissues.
动物没有脂肪酸合成酶不能生存,所以在此研究中的老鼠能够在绝大多数的组织中产生替代物质。
These mouse experiments suggest targeting fatty acid synthase in macrophages may provide a potential treatment strategy for humans.
这些老鼠实验暗示锁定巨噬细胞中的脂肪酸合成酶可能为人类提供潜在治疗策略。
In this study, the research team inhibited atherosclerosis in mice by interfering with production of a substance called fatty acid synthase.
在这项研究中,研究团队干扰一种叫做脂肪酸合成酶物质的产物,抑制了小鼠的动脉粥样硬化。
Fatty acid synthase (FAS) is reported as a potential new therapeutic target for obesity. However, there are limited known FAS inhibitors presently.
最新报道脂肪酸合酶(FAS)是治疗肥胖症的潜在靶部位,但目前已知的FAS抑制剂还很少。
CLA may inhibit the enzymes, lipoprotein lipase(LPL), stearoyl-CoA desaturase(SCD), fatty acid synthase(FAS)and so on, which are related to lipid metabolism.
抑制脂肪代谢相关酶脂蛋白脂酶、硬脂酰辅酶A 脱氢酶、脂肪酸合成酶等的活性来产生降脂作用。
Objective to study the effects of baicalein on differentiation of 3t3-l1 murine preadipocytes into adipocytes and on the activities of fatty acid synthase (FAS).
目的研究黄芩素对3 T3- L 1小鼠前脂肪细胞分化及对脂肪酸合成酶活性的影响。
Only recently has it been appreciated that C75, the inhibitor of fatty acid synthase can make mice lose weight via reducing food intake and increasing energy consumption.
近年研究发现,脂肪酸合成酶抑制剂C75可以抑制小鼠进食量,增加外周能量消耗,因而具有减轻小鼠体重的作用。
Background: Overexpression of the fatty acid synthase (FASN) gene has been implicated in prostate carcinogenesis. We sought to directly assess the oncogenic potential of FASN.
背景:脂肪酸合成酶(FASN)过表达参与了前列腺癌的发生。我们直接研究FASN的致癌潜能。
"It may be possible, for example, to take macrophages out of humans, inhibit fatty acid synthase in those cells, and then infuse the macrophages back into the same person," he says.
“也许有可能,例如说,将人类的巨噬细胞提取出来,抑制这些细胞中的脂肪酸合成酶,然后再将这些细胞注入同一个人的身体中,”他说。
"It may be possible, for example, to take macrophages out of humans, inhibit fatty acid synthase in those cells, and then infuse the macrophages back into the same person," he says.
“也许有可能,例如说,将人类的巨噬细胞提取出来,抑制这些细胞中的脂肪酸合成酶,然后再将这些细胞注入同一个人的身体中,”他说。
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