Objective: To study the effects of high concentration glucose on islet cell apoptosis and apoptosis related genes, and discuss the glucose toxicity and its molecular mechanism.
目的:观察高浓度葡萄糖体外对胰岛细胞凋亡及凋亡相关基因表达的影响,探讨葡萄糖毒性及其分子机制。
AIM: to investigate the effect of high glucose with various concentration on apoptosis of human lens epithelial cells.
目的:研究不同浓度的高糖对人晶状体上皮细胞凋亡的作用。
Conclusion: L-carnitine of certain concentration can promote the proliferation and inhibit the apoptosis of HPMC under high glucose condition.
结论:高糖条件下一定浓度的左旋肉碱可以促进人腹膜间皮细胞增殖、减少其凋亡。
Taking L-threonine Producing strain TRFC as bacterial strains, the effect of the growth factors and culture conditions on the L-threonine fermentation under high glucose concentration was studied.
以L -苏氨酸生产菌TRFC为供试菌株,研究了高葡萄糖浓度下各种生长因子和培养条件对L -苏氨酸发酵的影响。
AIM: To determine whether high concentration of glucose inhibits endothelium-dependent vasorelaxation of rabbit aortic artery and possible mechanisms.
目的:研究高浓度葡萄糖是否能抑制兔胸主动脉内皮依赖的血管舒张以及可能的机制。
Exposure of islet cells to high concentration of glucose, dexamethosone and palmitate can reduce the expression of PDX-1, therefore affects the insulin synthesis of islet cells.
高浓度的葡萄糖、糖皮质激素、脂肪酸可抑制PDX-1蛋白的表达,从而抑制胰岛细胞的胰岛素分泌功能。
CONCLUSION: High concentration of glucose inhibited endothelium-dependent vasorelaxation and this effect was unlikely mediated through activating oxygen-derived free radical production.
结论:高浓度葡萄糖抑制内皮依赖的血管舒张,这种作用不是通过增加氧自由基的产生介导的。
The purpose of this paper was to study the effect of benfotiamine on proliferation and apoptosis of bovine retinal capillary endothelial cells cultured in high concentration of glucose.
目的研究苯磷硫胺对体外高糖环境中培养的牛视网膜毛细血管内皮细胞的生长及细胞凋亡的影响。
It was concluded that high concentration of sucrose, glucose and fructose was toxic to the microspores.
认为高浓度的蔗糖葡萄糖以及葡萄糖与果糖混合糖源对小孢子有毒害作用。
RESULTS: Cells, exposed to high concentration D-glucose, were crude with clear profiles and bright granules in the plasma.
结果:高糖组细胞粗糙,轮廓增强,细胞内有许多发亮的颗粒;
Conclusion High glucose can stimulate the proliferation of retina cells, the mechanism maybe lies in decreasing the concentration of NO.
结论高浓度葡萄糖可使视网膜混合培养细胞增殖,其机制可能部分与NO产生量减少有关。
Conclusion High glucose can stimulate the proliferation of retina cells, the mechanism maybe lies in decreasing the concentration of NO.
结论高浓度葡萄糖可使视网膜混合培养细胞增殖,其机制可能部分与NO产生量减少有关。
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