OBJECTIVE To investigate the protective effects of M3 receptor agonist pilocarpine on myocardial ischemia-reperfusion injury in isolated rat hearts.
目的研究M3受体激动剂毛果芸香碱对离体大鼠心肌缺血再灌注损伤的保护作用。
Methods: Myocardial ischemic and reperfusion isolated heart model was established by temporary occlusion of the coronary artery of SD rats.
方法:用离体兔心灌注和SD大鼠在体心脏冠状动脉结扎,制造心肌缺血后再灌注两种模型。
Objective To observe the delayed protective effects of ramipril on myocardial ischemic-reperfusion injury in isolated rat hearts and explore the possible mechanisms.
目的探讨雷米普利预适应对大鼠离体心脏缺血-再灌注损伤的延迟性保护作用及机制。
Object: To investigate the effect of Aiweixin on the heart function, arrhythmia, LDH, formazan content and myocardial apoptosis of isolated rat heart during ischemia and reperfusion.
目的:观察爱维心对离体缺血再灌注过程心脏心功能、心律失常、心肌酶、心肌细胞活性及其心肌细胞凋亡的影响,并探讨其可能的作用机制。
Object: To investigate the effect of Aiweixin on the heart function, arrhythmia, LDH, formazan content and myocardial apoptosis of isolated rat heart during ischemia and reperfusion.
目的:观察爱维心对离体缺血再灌注过程心脏心功能、心律失常、心肌酶、心肌细胞活性及其心肌细胞凋亡的影响,并探讨其可能的作用机制。
应用推荐