• Plasma concentration decline with a half-life of about 2 hours.

    等离子的浓度下降一半,约2小时。

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  • AUMC is the area under the first moment of the plasma concentration-time curve.

    其中AUMC是指一阶矩血浆浓度时间曲线下面积。

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  • OBJECTIVE: To determine plasma concentration of irbesartan by HPLC with fluorescence detection.

    目的:建立以HPLC -荧光检测法测定人血浆中厄贝沙坦浓度的方法。

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  • OBJECTIVE To study the influence of oral antibiotics on the scutellarin plasma concentration in rats.

    目的研究口服抗生素药物对中药有效成分血药浓度的影响。

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  • OBJECTIVE:To establish a reversed-phase HPLC assay to monitor the plasma concentration of Amphotericin B.

    目的:采用反相高效液相色谱法测定两性霉素B的血药浓度,用于该药的治疗药物监测。

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  • In the saline-treated group, the plasma concentration of rocuronium and depth of block remained constant.

    在盐水处理组,血桨中罗库溴铵浓度及阻滞的深度保持不变。

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  • But the administration makes the plasma concentration change enormously, which is not suitable in treatment.

    但这种给药方式使血药浓度波动很大,不利于临床的有效治疗。

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  • There was negative correlation between the plasma concentration of Fg and high-density lipoprotein cholesterol.

    纤维蛋白 原浓度与高密度脂蛋白胆固醇浓度呈负相关。

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  • Objective To explore relation between the plasma concentration of et and NO and the process of the brain edema after ICH.

    目的探讨血浆内皮素(et)、一氧化氮(NO)浓度与脑出血后脑水肿的关系。

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  • No effects of risperidone on lithium or valproate exposure were observed, despite a 20% increase in valproate peak plasma concentration.

    我们没有观察到利培酮合用锂盐或丙戊酸钠的不良反应,尽管在丙戊酸钠上血浆浓度峰值增加20%。

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  • OBJECTIVE: To prepare the long acting nifedipine tablet, determined dissolution rate and plasma concentration of nifedipine in dog.

    目的:制备硝苯地平缓释片并测定释放度和犬血药浓度。

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  • METHODS The plasma concentration of 5-isosorbide mononitrate and salicylic acid were determined by GC and HPLC method respectively.

    建立了一种用高分辨气相色谱法测定人血浆中单硝酸异山梨酯含量的方法。

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  • After equilibrium is attained, drug concentrations in tissues and in extracellular fluids are reflected by the plasma concentration.

    达到分布平衡后,便可通过血浆浓度反映组织和细胞外液的药物浓度。

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  • The plasma concentration of D-D was measured by enzyme-linked immunosorbent assay(ELISA) in 45 patients with hematologic malignancies.

    采用酶联免疫吸附测定(ELISA)双抗夹心法对4 5例恶性血液病进行了D D测定。

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  • Objective To investigate the effect of acute hypervolemic hemodilution (AHHD) on plasma concentration of propofol by constant infusion.

    目的观察急性高容血液稀释后恒速输注异丙酚血药浓度的变化。

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  • Plasma concentration time data derived from the experiment were analyzed by non compartmental methods based on statistical moment theory.

    试验所得的血浆浓度时间数据采用非房室模型统计矩原理分析处理。

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  • Objective To study the changes of plasma concentration of BNP and ET-1 in patients with congestive heart failure and the correlation between them.

    目的探讨血浆脑钠肽(BNP)和内皮素1(ET-1)在心力衰竭(心衰)患者中的浓度变化及二者的相关性。

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  • This parameter provides a reference for the plasma concentration expected for a given dose and for the dose required to produce a given concentration.

    该参数可以为预期一次剂量后的血浆浓度以及预计达到某个血药浓度所需要的剂量提供参考。

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  • Using HPLC to detect the plasma concentration of MP and MPHS at different time after intravenous injection Methylprednisolone Sodium Succinate (MPS) in SD rats.

    采用HPLC法检测大鼠静脉注射甲基强的松龙琥珀酸钠(MPS)后不同时间血浆中MP及MPHS的浓度。

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  • BIS, mean artery pressure (MAP), heart rate (HR), plasma concentration of propofol, and the total induction dose of propofol when BIS reduced to 50 were recorded.

    记录各时间点的BIS、平均动脉压(map)、心率(HR)、丙泊酚血药浓度以及BIS降至50时的丙泊酚麻醉诱导总量。

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  • Bioavailability determinations based on the peak plasma concentration can be misleading, because drug elimination begins as soon as the drug enters the bloodstream.

    单靠峰时血浆浓度来确定生物利用度会导致误解,因为药物一进入血流就会开始药物消除。

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  • Brain natriuretic peptide (BNP) is mainly secreted from the cardiac ventricles and its plasma concentration is positive correlated with the pressure or volume overload.

    脑钠肽(BNP)主要由心室分泌,血浆浓度与心室体积或压力负荷程度呈正比。

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  • The plasma concentration of thrombomodulin (TM) were measured in 29 cases of acute non-lymphocytic leukemia (ANLL). Plasma TM level significantly increased in ANLL patients.

    本文对29例急性非淋巴细胞白血病(ANLL)患者的血浆血栓调节蛋白(TM)水平进行检测,发现ANLL组血浆TM水平比正常组明显升高。

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  • The blood samples were collected from the rats and the plasma concentration was measured by SPE-HPLC. The pharmacokinetic parameters and absolute bioavailability were evaluated.

    采用固相萃取-高效液相色谱法测定大鼠血浆中药物浓度,计算药动学参数和生物利用度。

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  • Results: the average plasma concentration of 5-fu in right hepatic vein was higher than that in the other two locations and the duration of high concentration of 5-fu was longer.

    结果:肝右静脉血浆5—FU平均血药浓度明显高于其它两个部位的血药浓度,且持续时间长。

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  • OBJECTIVE To investigate the association between valproic acid (VAP) plasma concentration at steady state (Css) and CYP2C19 gene polymorphisms for better individualized medication.

    目的:寻找丙戊酸药物浓度与CYP2C19基因多态性的关系,以便临床根据患者的基因型进行个体化给药。

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  • Objective: To establish a numerical method for plasma concentration of drugs obeying parallel first order and Michaelis-Menten clearance kinetics by bolus intravenous administration.

    目的:获得(一级并行)米氏消除药物静脉注射给药时的血药浓度近似解。

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  • Objective To investigate the effect of stellate ganglion block (SGB) on the plasma concentration of noradrenaline (ne) in rabbits suffering from acute pain and the possible mechanism.

    目的观察星状神经节阻滞(SGB)对兔血浆去甲肾上腺素(NE)浓度的影响,探讨其治疗疼痛的可能机制。

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  • Objective To investigate the effect of stellate ganglion block (SGB) on the plasma concentration of noradrenaline (ne) in rabbits suffering from acute pain and the possible mechanism.

    目的观察星状神经节阻滞(SGB)对兔血浆去甲肾上腺素(NE)浓度的影响,探讨其治疗疼痛的可能机制。

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