• Low protein binding rate.

    蛋白结合率低。

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  • Plasma protein binding rate of lofexidine was (about) 38%.

    洛非西定的血浆蛋白结合率约为38%。

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  • The PKC activity was determined by competed protein binding method.

    竞争蛋白结合法测定PKC的活性;

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  • The serum protein binding rate in dogs was determined by dialysis method.

    用透析法测定药物的狗血浆蛋白结合率。

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  • The apparent volume of distribution is 0.15~0.31/kg and protein binding 30~40%.

    表观分布容积为0.15~0.31/kg、蛋白质结合率为30~4C%。

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  • OBJECTIVE To study the plasma protein binding rate of harmine hydrochloride.

    目的:测定盐酸去氢骆驼蓬碱的血浆蛋白结合率。

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  • Methods: Activity of PKC was determined by using competitive protein binding method.

    方法:应用竞争蛋白结合法检测PK c活性。

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  • OBJECTIVE To introduce the application of microdialysis technique in the study of drug-protein binding.

    目的介绍微透析技术在药物-蛋白结合研究中的应用。

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  • Objective To clone and bioinformatically analyze the full-length sequence of F protein binding protein 1 (FBP1).

    目的对命名为F蛋白结合蛋白1(FBP1)的未知基因,克隆其全长基因并进行生物信息学分析。

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  • The serum total thyroxine(T_4) contents of 49 Ganzhou White swine were determined by competitive protein binding.

    用竞争性蛋白结合法测定了49头赣州白猪的血清甲状腺素(T_4)含量。

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  • According to our results, it was concluded that the PK parameters differences between human and rat were not due to plasma protein binding.

    结果表明人与大鼠药代动力学参数的差异不是由蛋白结合率的差异所导致。

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  • Plasma protein binding influences distribution and the apparent relationship between pharmacologic activity and total plasma drug concentration.

    血浆蛋白的结合作用会影响药物的分布,并影响药理活性和总血浆药物浓度间的表观关系。

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  • This score enables ranking of different DNA binding sites given a protein binding site and vice versa and can be used in molecular design protocols.

    这评分使排名不同的DNA结合位点提供的蛋白质结合位点,反之亦然,可以用于分子设计议定书。

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  • The principle and regulation effect of high performance frontal analysis (HPFA) and its application in the study of drug-protein binding were reviewed.

    综述高效前沿分析法(HPFA)的原理、调节作用及其在药物与蛋白结合研究中的应用。

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  • The performance tests indicate that matrices have well macroporous structure, the protein binding capacity of the prepared anion adsorbent could increase 15 %;

    研究表明:复合基质具有良好的大孔结构,所制备的阴离子吸附剂的蛋白质吸附性能能提高15%;

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  • Mofeover, the negative result of s-100 protein binding to the nerves in the lesions is helpful in differentiating leprosy from tuberculosis and sarcoidosis sarcoidosis.

    此外病损中的神经组织呈s- 100蛋白标记阴性,这有助于麻风的鉴别。

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  • The purpose was to provide simple, robust, easy to implement and feasible approaches for drug-protein binding study in new drug design and therapeutic drug monitoring (TDM).

    其目的是为新药研究和治疗药物监测中研究药物-蛋白结合作用提供简单、耐用、易操作和可行的方法。

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  • The studies revealed that the resistance formation of rice stem borer was closely involved with the increase of detoxifying enzyme activity, target enzyme insensitivity and protein binding.

    已有研究表明:解毒酶活性升高、靶标不敏感性以及蛋白质的螯合作用与二化螟抗药性形成的关系密切。

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  • Conclusion: the method was simple and convenient. The protein binding rates and protein binding parameters of atropine sulfate and scopolamine hydrobromide were determined with the method effectively.

    结论:该方法简便易行,能够有效测定硫酸阿托品和氢溴酸东莨菪碱蛋白结合率及蛋白结合参数。

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  • The enzymes in question are histone acetyltransferase (which adds acetyl groups to proteins) and methylated DNA-binding protein-2 (which removes methyl groups from DNA).

    这两种酶是组蛋白乙酰转移酶(它能给蛋白质添加乙酰基)和甲基化dna结合蛋白- 2(它能把DNA上的甲基去除)。

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  • Red blood cells contains large amounts of haemoglobin – the protein that gives blood both its colour and its oxygen-binding capacity.

    红血球含有大量的血红素,这种蛋白质能和氧气结合并是血液呈现出红色。

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  • Isolation and identification the auxin binding protein is one of the major works in the studying of auxin receptor.

    分离、鉴定与生长素结合的蛋白是生长素受体研究中的一个重要方面。

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  • The portion of collagen protein incorporated in the graft is thought to be responsible for binding fibroblasts and osteoblasts in the material matrix.

    研究表明,移植物中的胶原蛋白部分与材料基质中的成纤维细胞和成骨细胞的结合密切相关。

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  • However, binding efficiency varies between flu strains, and that variation is partly determined by the receptor-binding site (RBS) within the hemagglutinin protein.

    然而,结合效率在不同毒株间存在差异,而且这种差异部分决定于血凝素蛋白中的受体结合位点。

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  • The enantiomer-specific structure of local anaesthetics has large impact on the pharmacokinetic process of these drugs, including absorption, protein-binding ratio, metabolism, and so on.

    药物对映体结构特异性对局麻药药代动力学的各个过程都有着很大影响,包括药物的吸收、蛋白结合率、代谢等。

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  • The protein has multiple subunits, each with a single ligand-binding site. Binding of ligand to one site decreases the binding affinity of other sites for the ligand.

    此蛋白质有多个亚基,每个亚基上有一个结合位点。配体与一个结合位点的结合降低了其它位点对配体的亲和力。

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  • Results The protein-binding rate of telmisartan to BSA was 93.8% and 94.1% respectively when incubated without and with hydrochlorothiazide.

    结果未加及加入氢氯噻嗪后的替米沙坦的蛋白结合率分别为93 8%和94 1%。

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  • Resistance to Bt toxins in some insects is linked with mutations that disrupt a toxin-binding cadherin protein.

    一些抗苏云金杆菌毒素的昆虫的抗性是和毒素结合钙粘蛋白的断裂相关。

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  • Resistance to Bt toxins in some insects is linked with mutations that disrupt a toxin-binding cadherin protein.

    一些抗苏云金杆菌毒素的昆虫的抗性是和毒素结合钙粘蛋白的断裂相关。

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