A noncompetitive antagonist prevents the agonist from producing any effect at a given receptor site.
非竞争性拮抗剂可阻止激动剂在特定受体部位产生任何效应。
A noncompetitive antagonist prevents the agonist from producing any effect at a given receptor site...
非竞争性拮抗剂可阻止激动剂在特定受体部位产生任何效应。
CONCLUSION Geniposide has the similar function as the agonist for GLP-1 receptor, including neurotrophic and neuroprotective effects.
结论京尼平苷具有与GLP - 1受体激动剂类似的神经营养和神经保护功能。
Since varenicline is only a partial agonist—not a full agonist—at the alpha4beta2 receptor site, it performs differently in smokers and nonsmokers, she said.
对alpha4beta2受体来说，既然伐伦克林仅是部分激动剂--不是完全激动剂，它对吸烟者和非吸烟者的作用是不同的，她说。
The medication, manufactured by Clinical Data Inc., is a combined serotonin reuptake inhibitor and 5ht1a agonist.
这些药物由“临床资料公司”(Clinical DataInc .)制造，是一个5 - HT再摄取抑制剂与5ht1a激动剂的化合物。
BYETTA is the first FDA-approved GLP-1 receptor agonist for the treatment of type 2 diabetes.
百泌达是FDA批准的治疗2型糖尿病的首个GLP- 1受体激动剂药物。
CD39 is phosphohydrolysing ATP and ADP, noting that ADP is the major agonist for platelet activation and aggregation, so CD39 has a pretty similar mechanism to antiplatelet therapies.
CD39可以磷酸化水解ATP成ADP，而ADP是血小板激活和聚集的主要激动剂，所以CD39具有抗血小板的作用。
Treatment of cells with the TLR-4 agonist, LPS, did not reduce trophoblast cell viability.
而以tlr - 4激动剂LPS处理的滋养层细胞并未有细胞活性下降。
This is most effective if a specific receptor blocking agent is available to counter the effects of a given agonist.
在这方面最有效的是利用特效的受体阻滞药对抗特定激剂的作用。
Objective: To evaluate and compare the effects of DA 1 receptor agonist, fenoldopam, rabbit pulmonary and mesenteric arteries.
目的：对比分析多巴胺1受体激动剂非诺多泮对兔肺动脉和肠系膜动脉的影响。
Different form antagonist that blocks the effect of agonist, inverse agonist produces opposite effect to that of agonist.
与阻断激动剂效应的拮抗剂不同，反向激动剂产生的效应与激动剂相反。
OBJECTIVE To investigate the protective effects of M3 receptor agonist pilocarpine on myocardial ischemia-reperfusion injury in isolated rat hearts.
目的研究M3受体激动剂毛果芸香碱对离体大鼠心肌缺血再灌注损伤的保护作用。
Objective to observe the effect of excitatory amino acids receptor agonist on the onset of puberty in female rats.
目的研究兴奋性氨基酸受体激动剂对雌性大鼠青春期启动的影响。
The enhanced effect of PCP was attenuated by atypical antipsychotics and glycine agonist, but not by the typical antipsychotics.
应用非典型性抗精神病药物和甘氨酸位点激动剂可以改善PCP诱导的不动增加，但典型性抗精神病药物无效。
Objective: to study the protecting effect of delayed preconditioning with A1 selective adenosine receptor agonist in donor heart preservation.
目的：探讨腺苷a1受体激动剂延迟预处理对大鼠心脏的保护效果。
AIM: to investigate the role of protease-activated receptor-2 (PAR-2) agonist in the formation and pathogenesis of stress ulcer.
目的：探讨大鼠蛋白酶激活受体- 2在应激性溃疡中的作用。
The secretion of progesterone was assayed by rad ioimmunoassay. The results showed that GABA stimulated progesterone secretion , GABA agonist muscimol had the same effect.
结果显示GABA促进大鼠黄体化颗粒细胞孕酮分泌，蝇覃醇有同样作用。
Direct injection of an adenosine A1 receptor agonist replicated the analgesic effect of acupuncture.
直接注射腺苷a 1受体拮抗剂能够复制针灸的镇痛效果。
To investigate the role of cytokines, we blocked cytokine release by using GTS-21, a selective agonist of the 7 nicotinic acetylcholine receptor.
为研究细胞因子的作用，我们使用GTS - 21(烟碱乙酰胆碱受体7的一种选择性激动剂)来阻断细胞因子的释放。
The present invention provides for novel compounds of Formula (I) and pharmaceutically acceptable salts and co-crystals thereof which have glucagon receptor antagonist or inverse agonist activity.
本发明提供了具有胰高血糖素受体拮抗剂活性或反向激动剂活性的、新颖的式i化合物及其药学上可接受的盐和共晶体。
The pharmaceutical composition useful in this invention comprises a P2Y receptor agonist with enhanced resistance to extracellular hydrolysis, such as dinucleoside polyphosphate compounds.
所述对本发明有效的药物组合物含有对胞外水解有增强抗性的P2Y受体激动药，如二核苷酸多磷酸化合物。
If you could get a clever leptin agonist molecule then there is of course huge potential for the treatment.
如果我们能够研发出“更聪明的药物”，比如瘦素受体激动剂，那么它肯定有巨大的治疗潜力。
The P2Y receptor agonist may be administered with therapeutic and adjuvant agents commonly used to treat edematous retinal disorders.
上述P 2y受体拮抗剂可以和通常用于治疗水肿性视网膜疾病的治疗剂和佐剂一起施用。
The invention relates to a multi- peptide agonist vitro screening method of the glucagon peptide-1 receptor and the screened multi- peptide.
本发明涉及胰高血糖素样肽-1受体的多肽类激动剂的体外筛选方法及筛选得到的 多肽。
VPAC1 agonist displayed more effective effects than VIP on body weight, plasma glucose, glucose tolerance, plasma insulin, the weight of viscera.
而VPAC1激动剂在体重、血糖、糖耐量、胰岛素浓度及内脏净重等方面的治疗效果更为明显。
Administration of the RXR agonist 9-cis-retinoic acid to demyelinated cerebellar slice cultures and to aged rats after demyelination caused an increase in remyelinated axons.
向脱髓鞘的小脑切片培养物和脱髓鞘后的衰老大鼠给予RXR激动剂9-顺式-视黄酸能够增加轴突髓鞘再生。
BYDUREON and BYETTA belong to the glucagon-like peptide-1 (GLP-1) receptor agonist class of medications.
BYDUREON和百泌达(BYETTA)都属于胰高血糖素样肽(GLP - 1)受体激动剂类药物。
Conclusions The R PIA, a stable specific adenosine A 1receptor agonist, may mediate delayed myocardial preconditioning which reduces significantly the infarct size of myocardium in rats.
结论RPIA可使大鼠在体心脏产生延迟预适应（显著降低心肌梗死范围） ；
Conclusions The R PIA, a stable specific adenosine A 1receptor agonist, may mediate delayed myocardial preconditioning which reduces significantly the infarct size of myocardium in rats.
结论RPIA可使大鼠在体心脏产生延迟预适应（显著降低心肌梗死范围） ；
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