• Cell Cycle Progression through the cell division cycle and transitions between various phases are regulated by using CDC25 phosphatases to activate specific cyclin-dependent kinase(CDK) complexes.

    细胞分裂周期运行不同时转换通过CDC25磷酸酶去磷酸化和激活周期蛋白依赖性激酶CDK)复合物来调控

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  • Cyclin D1 which functions as a mitogenic sensor and allosteric activator of CDK4/6, is one of the more frequently altered cell cycle regulators in cancers.

    细胞周期蛋白D1作为一个能促进有丝分裂CDK4变构激活剂,癌症频繁变化细胞周期调节子。

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  • Cyclin D1 encodes the regulatory subunit of a holoenzyme that phosphorylates and inactivates the retinoblastoma protein and promotes progression through the G1-S phase of the cell cycle.

    周期d 1编码一种调节亚单位酶利用蛋白磷酸化视网膜母细胞瘤蛋白,通过细胞周期G 1 - S期促进肿瘤进展恶化。

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  • Cyclin D1 encodes the regulatory subunit of a holoenzyme that phosphorylates and inactivates the retinoblastoma protein and promotes progression through the G1-S phase of the cell cycle.

    周期d 1编码一种调节亚单位酶利用蛋白磷酸化视网膜母细胞瘤蛋白,通过细胞周期G 1 - S期促进肿瘤进展恶化。

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