Erythroid-specific 5-aminolevulinate synthase (ALAS2) catalyzes the rate-limiting step in heme biosynthesis of erythroid cells.
红系特异的5-氨基酮戊酸合成酶（ALAS2）是红系细胞血红素生物合成的限速酶。
Methods Induce the differentiation of erythroleukemia cell line HB60-5 to mature erythroid cells by altering the culture condition and plot a cell growth curve.
方法利用红白血病细胞株hb60 - 5的生长特性，通过改变培养条件，促使细胞向成熟细胞分化。
The absence of ALAS2 leads to maturation arrest of primitive erythroid cells. Heritable mutations of ALAS2 gene are responsible for the human X-linked sideroblastic anemia (XLSA).
ALAS2的缺失能导致红细胞发育的停滞，ALAS2基因的遗传性突变能引起X-连锁的成高铁红细胞贫血（XLSA）。
Objective: to understand the changes in hematopoietic growth factor receptors during erythroid differentiation of pluripotent cells.
目的：了解多潜能造血祖细胞向红系分化过程中造血因子受体的改变。
Objective: to understand the changes in hematopoietic growth factor receptors during erythroid differentiation of pluripotent cells.
目的：了解多潜能造血祖细胞向红系分化过程中造血因子受体的改变。
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