Pathology: p53 tumor suppressor gene mutation, loss of heterozygosity (LOH) at 11p15 locus. PAX-FKHR gene fusion.
病理学:p53肿瘤抑制基因突变,第11p15基因座杂和性丢失。
Using gene fusion technology, polypeptide fusion tags can be engineered into target proteins at the genetic level.
多肽融合标签能够赋予目标蛋白新的特性,便于目标蛋白的定位、追踪、纯化以及结构和相互作用研究。
The principles, operation and applications of site-directed mutagenesis, gene fusion technology, and post-translational modification methods were introduced emphatically.
着重阐述了基因定点突变技术、基因融合技术和翻译修饰技术等新兴定点固定化技术的原理、特点和操作。
Methods Based on the usefulness of gene fusion analysis for transcriptional analysis, two kinds of plasmids and integrant mutant strains were developed for the systemic study of PQS.
方法基于基因融合分析在转录研究中的实用性,构建了两种PQS相关对照质粒和整合突变株。
In 2007 a group of researchers discovered that the fusion of two normally independent genes, EML4 and ALK, into one aberrant gene seems to drive the formation of tumours.
2007年一个研究小组发现,两种普通基因(EML4和ALK)和一个异常化基因的融合能形成肿瘤。
Objective:To study on relationship between of BCR/ABL fusion gene expression and TCM syndrome classification in the patient of chronic myelogenous leukemia(CML).
目的:探讨慢性粒细胞白血病(CML)患者BCR/ABL融合基因表达与中医辨证分型的关系。
After that, introducing weight gene, syncretized PID and fuzzy control's outputs by adding weight. At last, the result of fusion was output to object controlled.
之后引入加权因子,采用加权的方法将PID和模糊控制各自的输出进行融合,将融合的结果最后输出到被控对象上。
The secretion expression vector of fusion gene in E. coli has constructed by fussing the proinsulin gene to the gene of staphylococcal protein a.
将胰岛素原基因融合到金色葡萄球菌蛋白a的基因上,构建成大肠杆菌中基因融合的外分泌表达载体。
The tyrosine kinases expressed by BCR-ABL fusion gene can cause cell proliferation, adhesion and survival natural change, several kinds of tumors can be caused by it.
BCR -ABL融合基因表达出的酪氨酸激酶能引起细胞增殖、黏附和生存性质的改变,导致多种肿瘤的产生。
Conclusion The GRA7 gene may be expressed as a GST fusion protein in E. coli.
结论GRA7基因在大肠埃希菌中以gst融合蛋白的形式得到表达。
To construct a recombinant plasmid containing protein transduction domain (PTD) and brain derived neurotrophic factor (BDNF) fusion gene and express in e.
构建含蛋白转导结构域(PTD)与脑源性神经营养因子(BDNF)融合基因的质粒,并在大肠肝菌中表达。
Objective: To clone and express the gene of human enterokinase light chain which would be used in the cleavage and purification of fusion proteins.
研究目的:克隆表达人肠激酶轻链编码基因,以期应用于融合蛋白的切割与纯化。
The specific chromosome and fusion gene are regarded as marker of leukemia, and helpful in leukemia diagnosis, evaluating prognosis, monitoring of treatment and minima residual leukemia.
特定的染色体和融合基因可作为白血病的标志物,对白血病的诊断、预后估计、监测治疗和微小残留白血病等方面具有一定的价值。
Aim: To express the whole length fusion protein of human IRGMa and prepare high quality rabbit anti-human immune-related gene guanosine triphosphate (IRGM) polyclonal antibody.
目的:表达人免疫相关鸟苷三磷酸酶基因(IRGM) a全长融合蛋白,制备高质量的兔抗人IRGM多克隆抗体。
Results: The CAT gene was cloned correctly and it's fusion protein was expressed in E.
结果:成功克隆了CAT的基因片段,并在大肠杆菌中得到其融合蛋白的表达。
Conclusion KDR promoter may regulate the CDglyTK fusion gene system to selectively kill the KDR-expressing SCG7901 cells and to induce the cell apoptosis.
结论KD R启动子可以调控融合基因体系选择性地杀伤人胃癌scg7901细胞,并且该体系可以诱导胃癌细胞凋亡。
Objective: to clone the gene of fructose binding protein BL0033 from Bifidobacterium longum NCC2705, and express and purify fusion protein GST-BL0033 in e.
目的:克隆长双歧杆菌ncc 2705株果糖结合蛋白bl 0033的基因,利用大肠杆菌表达GST -BL 0033融合蛋白并纯化。
This study was aimed to explore the relationship of 6; 9 chromosome translocation with DEK-CAN fusion gene expression in patients with acute myeloid leukemia (AML) and its clinical significance.
本研究旨在探讨急性髓系白血病(aml)患者6;9染色体易位与DEK - CAN融合基因表达之间的关系及临床意义。
Conclusion 2cvn fusion gene was successfully constructed and highly expressed.
结论已成功构建了2cvn融合基因,并获得高效表达。
Objective: To study the influence of tetracycline-controlled system on expression of the DT390-VEGF165 fusion gene in human gastric carcinoma cell.
目的:研究四环素调控系统对DT390-VEGF165融合基因在人胃癌细胞中表达的影响。
The most commonly used gene delivery methods include: physical method, chemical methods, fusion method and gene gun etc.
目前基因转运方法有许多种,其中包括物理方法、化学方法,融合法,基因枪等。
Objective To study the frequency and clinical significance of transloation, ets, leukemia-acute myeloblasticleukemia1 (TEL-AML1) fusion gene in children with acute lymphoblastic leukemia (ALL).
目的研究TEL-AML1融合基因在儿童急性淋巴细胞白血病(ALL)的发生率及其临床意义。
Objective to detect SYT-SSX fusion gene transcripts in fresh-frozen synovial sarcoma specimens and analyze the correlation between histological phenotypes and SYT-SSX subtypes.
目的检测滑膜肉瘤新鲜冰冻标本中的SYT -SSX融合基因,分析融合基因亚型与病理表型之间的关系。
Gene markers which are used to detect minimal residual disease(MRD)include fusion genes(FG), aberrant genes and some genes with high expression in leukemia disease.
残留白血病检测的基因标志可大致分为融合基因、变异基因和一些白血病中表达增高的基因。
Objective: to detect the expression of the fusion epitopes gene of foot-and-mouth disease virus (FMDV) in vitro.
目的:在体外检测口蹄疫病毒融合表位基因的表达。
The application of the techniques of large_scale cell culture, somatic cell fusion and gene transformation will greatly change the traditional mode of production and breeding of sweet potato.
细胞大规模培养、体细胞融合、基因转导等技术的研究和应用,可望从根本上改变甘薯传统的生产和育种模式。
Objective To construct recombinant plasmid with human atrial natriuretic peptide (ANP) gene in fusion form for stable and high level expression of genetic engineering product ANP in E. coli system.
目的构建以融合蛋白形式在大肠杆菌中高效表达心钠素的重组质粒,稳定高效地获得基因工程产品心钠素。
Conclusion: detection of BCR-ABL fusion gene by one step RT-PCR has excellent sensitivity and specificity. The method is simple and rapid, and is exactly used to clinic detection.
结论:一步法rt - P CR检测BCR - ABL融合基因有很好的灵敏度和特异性,操作简便、快速,特别适用于临床检测。
Conclusion: detection of BCR-ABL fusion gene by one step RT-PCR has excellent sensitivity and specificity. The method is simple and rapid, and is exactly used to clinic detection.
结论:一步法rt - P CR检测BCR - ABL融合基因有很好的灵敏度和特异性,操作简便、快速,特别适用于临床检测。
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