• Pathology: p53 tumor suppressor gene mutation, loss of heterozygosity (LOH) at 11p15 locus. PAX-FKHR gene fusion.

    病理学p53肿瘤抑制基因突变第11p15基因座杂和丢失

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  • Using gene fusion technology, polypeptide fusion tags can be engineered into target proteins at the genetic level.

    多肽融合标签能够赋予目标蛋白新的特性,便于目标蛋白定位、追踪、纯化以及结构和相互作用研究。

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  • The principles, operation and applications of site-directed mutagenesis, gene fusion technology, and post-translational modification methods were introduced emphatically.

    着重阐述基因定点突变技术、基因融合技术翻译修饰技术等新兴定点固定化技术原理、特点和操作

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  • Methods Based on the usefulness of gene fusion analysis for transcriptional analysis, two kinds of plasmids and integrant mutant strains were developed for the systemic study of PQS.

    方法基于基因融合分析转录研究中的实用性,构建了PQS相关对照质整合突变

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  • In 2007 a group of researchers discovered that the fusion of two normally independent genes, EML4 and ALK, into one aberrant gene seems to drive the formation of tumours.

    2007年研究小组发现种普通基因(EML4ALK)和异常化基因融合形成肿瘤

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  • Objective:To study on relationship between of BCR/ABL fusion gene expression and TCM syndrome classification in the patient of chronic myelogenous leukemia(CML).

    目的探讨慢性粒细胞白血病CML患者BCR/ABL融合基因表达中医辨证型的关系

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  • After that, introducing weight gene, syncretized PID and fuzzy control's outputs by adding weight. At last, the result of fusion was output to object controlled.

    之后引入加权因子,采用加权方法将PID模糊控制各自输出进行融合,将融合的结果最后输出被控对象上。

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  • The secretion expression vector of fusion gene in E. coli has constructed by fussing the proinsulin gene to the gene of staphylococcal protein a.

    胰岛素基因融合金色葡萄球菌蛋白a基因上,构建大肠杆菌中基因融合的外分泌表达载体

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  • The tyrosine kinases expressed by BCR-ABL fusion gene can cause cell proliferation, adhesion and survival natural change, several kinds of tumors can be caused by it.

    BCR -ABL融合基因表达出的酪氨酸激酶引起细胞增殖黏附生存性质改变,导致多种肿瘤的产生。

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  • Conclusion The GRA7 gene may be expressed as a GST fusion protein in E. coli.

    结论GRA7基因大肠埃希菌中以gst融合蛋白的形式得到表达

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  • To construct a recombinant plasmid containing protein transduction domain (PTD) and brain derived neurotrophic factor (BDNF) fusion gene and express in e.

    构建蛋白转导结构(PTD)源性神经营养因子(BDNF)融合基因的质,并大肠肝菌中表达

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  • Objective: To clone and express the gene of human enterokinase light chain which would be used in the cleavage and purification of fusion proteins.

    研究目的克隆表达激酶编码基因,以期应用融合蛋白切割纯化

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  • The specific chromosome and fusion gene are regarded as marker of leukemia, and helpful in leukemia diagnosis, evaluating prognosis, monitoring of treatment and minima residual leukemia.

    特定的染色体融合基因作为白血病标志物,对白血病的诊断预后估计、监测治疗微小残留白血病等方面具有一定的价值。

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  • Aim: To express the whole length fusion protein of human IRGMa and prepare high quality rabbit anti-human immune-related gene guanosine triphosphate (IRGM) polyclonal antibody.

    目的表达免疫相关鸟苷三磷酸酶基因(IRGM) a全长融合蛋白制备质量抗人IRGM多克隆抗体

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  • Results: The CAT gene was cloned correctly and it's fusion protein was expressed in E.

    结果:成功克隆CAT基因片段,并大肠杆菌中得到融合蛋白表达

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  • Conclusion KDR promoter may regulate the CDglyTK fusion gene system to selectively kill the KDR-expressing SCG7901 cells and to induce the cell apoptosis.

    结论KD R启动可以调控融合基因体系选择性地杀伤人胃癌scg7901细胞,并且体系可以诱导胃癌细胞凋亡

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  • Objective: to clone the gene of fructose binding protein BL0033 from Bifidobacterium longum NCC2705, and express and purify fusion protein GST-BL0033 in e.

    目的克隆长双歧杆菌ncc 2705株果糖结合蛋白bl 0033基因,利用大肠杆菌表达GST -BL 0033融合蛋白纯化

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  • This study was aimed to explore the relationship of 6; 9 chromosome translocation with DEK-CAN fusion gene expression in patients with acute myeloid leukemia (AML) and its clinical significance.

    研究旨在探讨急性髓系白血病(aml)患者69染色体易位DEK - CAN融合基因表达之间关系临床意义

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  • Conclusion 2cvn fusion gene was successfully constructed and highly expressed.

    结论成功构建2cvn融合基因,并获得高效表达

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  • Objective: To study the influence of tetracycline-controlled system on expression of the DT390-VEGF165 fusion gene in human gastric carcinoma cell.

    目的研究四环素调控系统DT390-VEGF165融合基因胃癌细胞表达影响

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  • The most commonly used gene delivery methods include: physical method, chemical methods, fusion method and gene gun etc.

    目前基因转运方法许多种,其中包括物理方法化学方法,融合,基因

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  • Objective To study the frequency and clinical significance of transloation, ets, leukemia-acute myeloblasticleukemia1 (TEL-AML1) fusion gene in children with acute lymphoblastic leukemia (ALL).

    目的研究TEL-AML1融合基因儿童急性淋巴细胞白血病ALL发生率及其临床意义

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  • Objective to detect SYT-SSX fusion gene transcripts in fresh-frozen synovial sarcoma specimens and analyze the correlation between histological phenotypes and SYT-SSX subtypes.

    目的检测滑膜肉瘤新鲜冰冻标本中的SYT -SSX融合基因分析融合基因亚型病理表型之间关系

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  • Gene markers which are used to detect minimal residual disease(MRD)include fusion genes(FG), aberrant genes and some genes with high expression in leukemia disease.

    残留白血病检测基因标志大致分为融合基因变异基因一些白血病表达增高的基因。

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  • Objective: to detect the expression of the fusion epitopes gene of foot-and-mouth disease virus (FMDV) in vitro.

    目的在体外检测口蹄疫病毒融合表位基因表达

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  • The application of the techniques of large_scale cell culture, somatic cell fusion and gene transformation will greatly change the traditional mode of production and breeding of sweet potato.

    细胞大规模培养体细胞融合基因转导等技术研究和应用可望从根本上改变甘薯传统生产育种模式

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  • Objective To construct recombinant plasmid with human atrial natriuretic peptide (ANP) gene in fusion form for stable and high level expression of genetic engineering product ANP in E. coli system.

    目的构建以融合蛋白形式大肠杆菌高效表达重组质粒稳定高效地获得基因工程产品素。

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  • Conclusion: detection of BCR-ABL fusion gene by one step RT-PCR has excellent sensitivity and specificity. The method is simple and rapid, and is exactly used to clinic detection.

    结论一步法rt - P CR检测BCR - ABL融合基因很好的灵敏度特异性,操作简便快速,特别适用临床检测。

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  • Conclusion: detection of BCR-ABL fusion gene by one step RT-PCR has excellent sensitivity and specificity. The method is simple and rapid, and is exactly used to clinic detection.

    结论一步法rt - P CR检测BCR - ABL融合基因很好的灵敏度特异性,操作简便快速,特别适用临床检测。

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