• Main Outcome Measures LOD score, STR, linkage analysis.

    主要指标LOD值,STR位点,连锁分析。

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  • The Web linkage analysis is playing a more and more important role in the researches on the World Wide Web.

    链接结构分析在万维网的很多研究领域发挥着越来越重要的作用。

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  • The data simulation results showed that the new linkage analysis method is optimal for small sample with strong linkage.

    数据模拟的结果表明新的方法更加适合小样本,及存在较强连锁关系的标记位点的情况。

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  • Objective to identify the disease locus in X - linked retinitis pigmentosa (XLRP) families using genetic linkage analysis.

    目的应用遗传连锁分析方法对X连锁型视网膜色素变性家系进行分析,确定其致病基因的所在位点。

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  • The disease gene is exactly located on the chromosome 5 and chromosome 12 through parameter and non-parameter linkage analysis.

    综合运用参数和非参数连锁分析,将致病基因定位到5号染色体和12号染色体上。

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  • United application of STR linkage analysis and multiplex allele specific PCR (MASPCR) in PKU genetic diagnosis was also analysed.

    同时分析了STR多态性与多重等位基因特异pcr (MASPCR)在PKU基因诊断中的联合应用。

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  • Conclusion: D12S1686 is such a valuable genetic marker that it can be used to gene linkage analysis and population genetics research.

    结论D 12s1686位点具有较高的杂合度和多态信息含量,在基因连锁分析和群体遗传学研究中具有重要的应用价值。

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  • For families without inversions, it is easier and more cost-effective to undertake linkage analysis of genetic polymorphism based on PCR.

    对于无倒位的家系,利用基因多态性进行遗传连锁分析较为有效可行。

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  • The first part of this dissertation focuses on the improvement of topic distillation and exploration with the aid of the linkage analysis.

    本文第一部分着重研究了利用互联网环境中超文本的链接结构信息改善和提高主题萃取和主题发现技术。

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  • Linkage map — a chromosome map showing the relative positions of genes and other DNA markers on the chromosomes, as determined by linkage analysis.

    连锁基因或遗传标记在染色体上的相对位置的线性图。

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  • Objective:The linkage analysis of gene polymorphism and diseases is the common method to study the molecular biological base of multigenic diseases.

    目的:基因多态和疾病的连锁分析是目前研究多基因疾病分子生物学基础的常用方法。

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  • After linkage analysis failed to locate susceptible genes of complex diseases like schizophrenia, it is a better way to process whole-genome association studies.

    用传统的家系连锁分析无法对精神分裂症这样的复杂疾病进行基因定位,而全基因组关联分析则为最终发现这些基因提供了较好的策略。

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  • Pedigree is one of the most general population structure in the genetic linkage analysis between human single genetic inheritance disease locus and genetic marker locus.

    在人类单位点致病基因与遗传标记基因的遗传连锁分析中,家系是应用得最普遍的一种群体结构。

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  • Up to date, on the bases of linkage analysis and cytogenetic analysis, the loci associated with microphthalmia have been identified and mutation analysis of the candidate loci are performed.

    迄今为止,用连锁分析和细胞遗传学方法对小眼球相关基因进行了基因定位并进一步对候选基因进行突变分析。

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  • Conclusions it suit to the small pedigree data. Multipoint linkage analysis can not only calculate the recombination and map distance, but also localize the disease gene to one side of the marker.

    结论适用于小家系资料的多位点连锁分析,不仅能算出致病基因与标记的重组率和遗传距离,而且能把致病基因定位至遗传标记的一侧。

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  • Conclusions it suit to the small pedigree data. Multipoint linkage analysis can not only calculate the recombination and map distance, but also localize the disease gene to one side of the marker.

    结论适用于小家系资料的多位点连锁分析,不仅能算出致病基因与标记的重组率和遗传距离,而且能把致病基因定位至遗传标记的一侧。

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