Inventions usually make a big difference to people's lives.
发明通常对人们的生活有很大的影响。
For small mammals, microclimates can make a big difference.
对于小型哺乳动物来说，微气候可以产生很大的影响。
Your choice of words can make a big difference, too.
你的用词也会产生很大的影响。
This little bit of support can sometimes make a big difference.
这种小小的支持有时会产生很大的影响。
Even a few hours a month can make a big difference in someone's life.
即使是一个月几个小时，也会对一个人的生活产生很大的影响。
Researchers at Duke University scrutinized more than 160 published studies and found an absence of strong evidence that any of these approaches can make a big difference.
杜克大学的研究人员详细核查了160多项已发表的研究，发现并没有强有力的证据表明这些方法中的任意之一能产生重大作用。
You have to be very exact in this plan, because a small mistake can make a big difference.
你做这项计划必须非常严谨，因为一个小错误就能造成天壤之别。
A little effort every day, you will make a big difference.
每天付出一点努力，你就会有很大的不同。
When it comes to climate change, can they make a big difference?
在气候变化问题上，他们能起到很大的作用吗？
She believed that such an experience would make a big difference to her 9-year-old boy's life.
她相信这样的一次经历会给9岁孩子的人生带来很大的改变。
That information can make a big difference in the campaigns and offers made to members of such a household.
由此获得的讯息可以极大地区分这样一个家庭中成员的活动和出价的不同。
A little bit of gratitude every day can, over time, make a big difference to our level of happiness and well being.
所以，每天都去感恩一些事情，慢慢的，我们的快乐和幸福指数将会有很大不同。
The trust factor of friends' Suggestions can make a big difference. Mr.
朋友建议中的信任因素则可能令结果完全不同。
There will be pain as tighter credit forces adjustments. But sensible, speedy international assistance would make a big difference.
为紧缩信贷而进行的调整必然会带来痛苦，但迅速的国际援助是明智之举，因为这会让结果大不相同。
While management attributes such as great communication skills make a big difference, pay factors in as well.
同时，因为良好的管理，使得良好沟通形成很大的差异，工资因素亦同。
And the choices you make, throughout your careers, through the next 50 years of your life, can make a big difference as well.
你们所作的选择，在你们的整个生涯中，在你们未来50年的生活中，也能够产生很大的影响。
Making a few simple changes, a few different choices can make a big difference in the long run.
从长远来看，做出一些简单的改变和一些不同的选择就可以产生很大的影响。
As children grow older than my patient, behavioral and other treatments can make a big difference.
当孩子长大到一定年龄之后，症状和治疗方式都会有很大的不同。
This can make a big difference to local prices.
这可以使它获得与当地的悬殊价差。
Researchers say there's a reason why even 30 minutes can make a big difference.
研究者说之所以仅30分钟就造成很大差别是有原因的。
For such smaller Banks, even modest inflows of new deposits can make a big difference.
对于这些小银行来说，即使小的新的资金流入也能够产生大的作用。
The trust factor of friends’ suggestions can make a big difference.
朋友建议中的信任因素则可能令结果完全不同。
The bottom line: Disaster is real and pervasive, but deeper collaboration plus smarter modeling make a big difference.
记住：灾难真实且无处不在，但深层协作与更为精妙的操作模式必会使之大为不同。
This small change in your mindset can make a big difference.
头脑中这一点小小的变化将会很大改变。
A few simple tips can make a big difference to your frame of mind.
一些简单的窍门就会给你的心情带来大大的改变。
But whether or not you do so doesn't seem to make a big difference.
但不论你是否选择这样做，都不会有什么太大的影响？
But I am confident that improving diet can make a big difference.
但是我坚信着改善饮食习惯是可以改变这种状况的。
But I am confident that improving diet can make a big difference.
但是我坚信着改善饮食习惯是可以改变这种状况的。
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