Giotto explored how to represent three dimensional space using light and shade.

VOA: special.2010.06.23

The people in the frieze are painted to look three- dimensional, like sculptures.

VOA: special.2010.01.27

"The three laureates have accomplished what many scientists thought impossible, namely to determine the three- dimensional structure of the molecular machine that makes all the proteins in a cell, the so-called ribosome,"

VOA: standard.2009.10.07