In remarks at the end of the Beijing talks, Chinese State Councilor Dai Bingguo said ensuring peace and security on the Korean peninsula is "critical" and urged the parties to "calmly and properly handle the issue and avoid escalation of tension."

VOA: standard.2010.05.25

Diabetics whose pancreas does not function properly, so don't make enough insulin, don't have enough insulin present for normal glucose metabolism so they can't handle sugars properly.

糖尿病人的胰脏功能失调,因此胰岛素分泌不足,影响了正常的血糖代谢,所以他们不能正常地调节血糖

耶鲁公开课 - 生物医学工程探索课程节选

That, at least, seems to handle the case of sleep properly.

这样一来似乎解决了睡眠问题。

耶鲁公开课 - 死亡课程节选