A state where it's closed, so imagine a channel with a lid on top of it; when it's closed nothing can go through the channel, when it's open then things can go through.

一种是闭合状态,想想一个有盖子的通道吧,当盖子合上的时候任何东西都不能通过,而打开时就畅通无阻

耶鲁公开课 - 生物医学工程探索课程节选

It would generate an electrical signal because it would - you'd open the ion channel and you would ion fluxes and you would change the membrane potential in just the way I described for the action potential.

它会产生一个电信号,因为--,离子通道会打开,产生离子流,膜电位会改变,像我讲动作电位时那样

耶鲁公开课 - 生物医学工程探索课程节选