Her father carried a heavy burden of responsibility.
她父亲肩负着重大责任。
On occasion, that can prove a heavy burden indeed.
有时，这的确可能成为非常沉重的负担。
Poverty on an old man's back is a heavy burden.
老而贫困，负担最沉。
When thousands of people are depending on you, that is a heavy burden.
当数千个人都依靠你的时候，这就成了一项繁重的负担。
The heavy burden bore him down.
她被沉重的家庭负担压垮了。
He staggered under a heavy burden.
他被沉重的担子压得摇摇晃晃。
His shoulders can bear a heavy burden.
他的双肩能负重。
They have an extra heavy burden to bear.
他们需要背负更重的担子。
Lays down the heavy burden, to make joyful.
放下沉重的包袱、做回快乐的自己。
The camel collapsed under its heavy burden.
骆驼被身上沉重的货物压垮了。
He shouldered the heavy burden of leadership.
他肩负着领导的重担。
His family imposed a heavy burden on his life.
他的家庭给他的生活带来沉重负担。
The old camel couldn't carry the heavy burden.
那头老骆驼驮不动那繁重的货物了。
The horse plodded slowly under the heavy burden.
驮着沉重的负担，这匹马沉重缓慢地走着。
Over time, these things have become a heavy burden.
日积月累，这些事都成为了沉重的负担。
What a heavy burden is a name that has become famous.
广为人知的名字是多么沉重的负担啊。
The everyday toil is a heavy burden on his aging body.
每天的劳累对他年迈的身体来说是个沉重的负担。
So I don't have a heavy burden in mind and can stay happy.
所以我并没有太大的压力，并且始终可以很快乐！
That is an especially heavy burden, naturally, for the elderly.
当然，这对老年人来说是非常大的负担。
We went over hills and rivers with the heavy burden on the shoulders.
我们扛着那沉重的柴禾翻山过河。
There being so large a population in so small a district is a heavy burden.
如此狭小的地区有如此众多的人口是一个沉重的负担。
By the loss of this friendship I found myself relieved from a heavy burden.
失去了他的友谊，我倒是卸下了一个沉重包袱。
In addition, they must bear the heavy burden of their expensive medical bills.
此外，他们必须承担高昂的医疗费。
If you carry a heavy burden in your heart, try to consult someone you can trust.
如果你心里有过于沉重的负担，试着告诉一个你信任的人，这样才能减轻你的痛苦。
Background: Lung cancer is the most common and heavy burden disease in the world.
研究背景：肺癌是目前全球最常见、疾病负担最重的恶性肿瘤。
Background: Lung cancer is the most common and heavy burden disease in the world.
研究背景：肺癌是目前全球最常见、疾病负担最重的恶性肿瘤。
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