I totally disagree with their opinion.
我完全不同意他们的观点。
As far as I'm concerned, I totally disagree with your opinion.
就我而言，我完全不同意你的看法。
Whatdo you do if you totally disagree with a request made by your manager?
如果你完全不同意你上司的某个要求，你怎么处理？
What do you do if you totally disagree with a request made by your manager?
如果你完全不同意你上司的某个要求，你怎么处理？ ？
ST: "Sorry mate but I totally have to disagree."
抱歉了兄弟，我完全不同意。
After pondering this opinion from several aspects, I totally agree (disagree) with you.
通过对此观点几个方面的考虑，我完全(不)同意。
After pondering this opinion from several aspects, I totally agree (disagree) with you.
通过对此观点几个方面的考虑，我完全(不)同意。
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