They alter the way it cleaves amyloid precursor protein.
它们改变了这个酶切割淀粉样蛋白前体的方式。
Amyloid plaques form when a molecule called amyloid precursor protein (APP) is chopped up by two enzymes known as beta-secretase and gamma-secretase.
当一种叫淀粉样前体蛋白（APP）的分子被两种酶——分别叫作贝塔-分泌酶和伽玛-分泌酶——切断时就形成了淀粉样斑块。
The causes for Alzheimer's disease are not known, but dysregulation of amyloid-precursor protein expression and beta-amyloid clearance is hypothesized (beta-amyloid cascade).
虽然导致老年痴呆症的原因还没有发现，但是有人假设其原因是淀粉样前提蛋白的调节异常和β-淀粉样蛋白的消失（β-淀粉样蛋白连锁反应）。
Aim: To investigate the changes of amyloid precursor protein (APP) transcriptional level at different ischemic times in rats' ischemic penumbra and core of cortices.
目的：研究大鼠局灶性脑缺血不同缺血时间皮质半暗带和中心区淀粉样前体蛋白(APP)在转录水平表达规律。
Amyloid precursor protein (APP) has been known to act as an important protein during the occurrence of Alzheimer's disease (AD).
淀粉样前体蛋白(APP)是阿尔茨海默氏病(AD)发病过程中有重要作用的蛋白。
Mutations in the gene encoding the human amyloid precursor protein (APP) cause familial AD, but there is not yet a clear understanding of the normal functions of APP family of proteins in neurons.
淀粉样肽前体蛋白(APP)基因突变导致家族性ad，但到目前还没有对APP家族蛋白正常功能的清楚认识。
Mutations in the gene encoding the human amyloid precursor protein (APP) cause familial AD, but there is not yet a clear understanding of the normal functions of APP family of proteins in neurons.
淀粉样肽前体蛋白(APP)基因突变导致家族性ad，但到目前还没有对APP家族蛋白正常功能的清楚认识。
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