RESULTS SODN inhibited the growth of CNE1 and CNE2Z cells as well as ASODN, and presented dose and time dependent manner.
结果端粒酶正义寡核苷酸与反义寡核苷酸一样可抑制鼻咽癌cne1和CNE2 Z细胞的生长,且呈剂量和时间依赖性。
Results The growth of human orbital rhabdomyosarcoma in nude mice was inhibited in the ASODN NP group obviously ( P< 0.05);
结果与其他两组相比,ASODN NP组肿瘤的生长明显受到抑制(P<0.05);
To study the inhibitory effect of bcl-2 antisense oligonucleotide (ASODN) combined with radiation on lung carcinoma cells NCI-H446.
研究Bcl - 2反义寡核苷酸联合照射对肺癌细胞的抑制作用。
Conclusion ASODN can suppress endothelial cell growth and inhibit tumor angiogenesis possibly by specifically blocking VEGF expression in thyroid carcinoma.
结论ASODN可通过特异性封闭甲状腺癌细胞VEGF表达,抑制内皮细胞生长,干扰肿瘤血管生成。
AIM: to investigate the effect of antisense oligonucleotides (ASODN) encoding telomerase reverse transcriptase (TERT) mRNA on thyroid carcinoma (TC) cell apoptosis.
目的:探讨端粒酶逆转录酶(TERT)的反义寡核苷酸(A SODN)对甲状腺癌(TC)细胞凋亡的影响。
The result showed that VEGF ASODN had obviously inhibitive effect on expression of VEGF in U937 cell, as compared with scrambled sequence and negative control (P<0.05).
结果显示,VEGFASODN对U937细胞的VEGF的表达有明显的抑制作用,与错义序列组和空白对照组相比有显著差异(P<0 .0 5 ) ;
Objective to investigate the effects of keratinocyte growth factor (KGF) and KGF receptor (KGFR) antisense oligonucleotide (ASODN) on cell cycle and apoptosis of HaCat cells.
目的研究角质形成细胞生长因子(KGF)及其受体(KGFR)反义寡核苷酸对KGF介导的细胞周期和凋亡变化的抑制作用。
Methods To set up HER-2 antisense oligodeoxynucleotides (ASODN) experimental group, sense oligodeoxynucleotides (SODN) group, folate acid (FA) group and 60Co irradiation control group.
方法实验分组如下:HER-2反义寡脱氧核苷酸组、HER-2正义寡脱氧核苷酸组、叶酸对照组和空白对照组。
ConclusionSTAT3 ASODN not only possess chemotherapeutic effect, but also can improve the sensitivity of tumor cells, making it a promising agent for future research and clinical application.
结论反义STAT 3既具有化疗效果,又具备放疗增敏作用,对提高肿瘤的放疗效果有良好的开发前景。
The lens posterior capsule was covered by a layer of lens epithelium in the control group, while the lens epithelium could hardly been observed on the lens posterior capsule in the ASODN group.
对照组晶体后囊前覆盖一层晶体上皮细胞,ASODN组晶体后囊前无明显晶体上皮细胞增殖。
The lens posterior capsule was covered by a layer of lens epithelium in the control group, while the lens epithelium could hardly been observed on the lens posterior capsule in the ASODN group.
对照组晶体后囊前覆盖一层晶体上皮细胞,ASODN组晶体后囊前无明显晶体上皮细胞增殖。
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