In a barn to be converted into a lab, he began foraging for his next big hit.
在一个即将被改造成实验室的谷仓里，他开始寻找下一个大热门。
You know, I gave a speech at Vassar 27 years ago. It was a really big hit.
27年前，我在瓦萨学院也做了个演讲，大获成功。
And what if you've already produced your big hit and don't know it yet?
而如果你已经有所作为自己还不知道的话该如何是好呢？
Stocks took a big hit Monday on heightened worries over Europe's debt crisis.
由于市场对欧洲债务危机的担忧加剧，美国股市周一遭受重挫。
Whether he gets that big hit or not, he runs to first base like his pants are on fire.
不管他有没有将球击中，他都会像裤子着了火一样拼命冲向一垒。
As a result, our self-esteem takes a big hit because we have lost our sense of direction.
结果因为失去了方向感，我们的自尊受到打击。
Is David Beckham more popular on or off the soccer field? Either way, "Beck" is a big hit in England.
大卫·贝克汉姆在球场上还是球场外更受欢迎？无论是哪一种身份，贝克·汉姆在英国都大受欢迎。
Its epicentre was at Prince William Sound, some 100 miles to the east, but Anchorage took a big hit.
震中在安克雷奇以东大约100英里的威廉王子湾，但安克雷奇也遭受重创。
The current IBF and IBO heavyweight champion is a big hit in both his native Ukraine and his adopted home of Germany.
当今的IBF以及IBO重量级冠军，对他的祖国乌克兰和他的居住地德国来说都是一个大人物。
After just a couple of years, Tchaikovsky wrote his first big hit, Romeo and Juliet, based on the play by Shakespeare.
不到几年时间，柴可夫斯基以莎士比亚的戏剧为蓝本，写下生平第一个广受欢迎的作品《罗密欧与朱丽叶幻想曲》。
As is the case elsewhere in Europe, the British economy is stagnant and real estate, in particular, is taking a big hit.
就像欧洲其他地方一样，英国经济停滞不前，房地产尤其受到冲击。
Some people at the bar joked that a new movie entitled the Toe Tapper should be filmed since Brokeback Mountain became a big hit.
酒吧里有些人说笑道，既然《断背山》这么受欢迎，也应该拍一部名为《足尖敲击者》的电影了。
If you're serious about your art, it's unlikely that you'll see your big hit coming; if your craft was that formulaic, it wouldn't be art.
如果你很严肃的对待自己的艺术，可能你不会预见到你的走红；而如果你的作品非常的程序化，那就不是艺术了。
"The Beatles special stamps promise to be a big hit with fans the world over when they go on sale in January 2007," a Royal Mail spokesman said.
皇家邮政的一位发言人说：“披头士乐队系列邮票将于明年1月发行，到时一定会在全世界披头士的歌迷中引起轰动。”
People are extremely happy before they have children and then their happiness goes down, and it takes another big hit when kids reach adolescence.
人们生孩子之前极为幸福，之后幸福度下降，当孩子进入青春期之后，幸福度会再次下降。
A big hit at this year's book fair was the Digital Bookstore, where visitors could read e-books by flipping through pages on slimly-designed touch screens.
今年书展的一大亮点是数码书店，在那里参观者可以通过浏览设计精细的触屏上的页面来阅读电子书。
The "alternative ice cream" offered to animals instead of their usual fare has been a big hit with large cats, apes and wolves, Zurich Zoo said in a statement.
苏黎世动物园在一份声明中表示，该园工作人员用这种另类冰淇淋代替那些动物们平时的食物，结果受到大型猫科动物、猿猴和狼等动物的巨大欢迎。
According to BCG, assets under management in China grew at a compound annual rate of 25% between 2002 and 2007, though the figure will have taken a big hit in 2008.
根据BCG的报告，从2002年到2007年，中国大陆在理财基金托管下的资产以每年25%的复利增长，尽管这一数据在2008年遭受到了重大打击。
Enjoyable remake of France "s big hit THREE MEN AND a CRADLE, about a trio of swinging bachelor roommates who suddenly find themselves custodians of an infant."
对法国影片《三个男人一个摇篮》的出色翻拍，讲述了几个生活多彩的单身汉突然要面对一个婴儿的故事。
But Amazon's much-vaunted cloud network took a big hit yesterday when it crashed, taking a host of web 2.0 companies - including Reddit, Quora, and Hootsuite - down with it.
但是，亚马逊引以为豪的云网络昨天大受打击，网络崩溃，导致许多web 2.0公司也跟着受累，包括Reddit、Quora及Hootsuite在内。
But Amazon's much-vaunted cloud network took a big hit yesterday when it crashed, taking a host of web 2.0 companies - including Reddit, Quora, and Hootsuite - down with it.
但是，亚马逊引以为豪的云网络昨天大受打击，网络崩溃，导致许多web 2.0公司也跟着受累，包括Reddit、Quora及Hootsuite在内。
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