Abstract: Response surface methodology was applied to optimize the drug loading rate of persimmon leaf total flavonoids sustained release pellets.
摘要:本文研究了响应面法优化柿叶总黄酮缓释微丸的载药量。
The drug loading rate, encapsulation efficiency, particle distribution and in vitro release of Lac-NCTD from liposomes were investigated, respectively.
考察了药物与磷脂的复合率,磷脂复合物脂质体的包封率,粒径大小和分布,以及体外释药特性。
Factors influencing the drug release rate, including drug loading, species and amount of additives, hardness, particle size were studied.
考察载药量、填充剂种类和用量、硬度、辅料粒径等因素对药物释放的影响。
Compared to microspheres with low water absorbing rate, the high batches had higher drug-loading rate and entrapment rate.
吸水度高的微球载药量和包封率较吸水度低的微球高。
The drug-loading rate of this chitosan-levofloxacin sustained-release microsphere is 43.88%. Its in vitro dissolubility is good.
该方法制备的左氧氟沙星-壳聚糖缓释微球载药量为43.88%,体外累积释放度的线形关系良好。
The particle size and distribution, appearance, mobility, characters, drug-loading rate and entrapment rate were used to evaluate the quality of the microspheres.
通过对微球粒径大小、粒径分布、表面形态、流动性、电性、浸水膨胀率、含量测定等项目的考察,检测微球的性能。
The particle size and distribution, appearance, mobility, characters, drug-loading rate and entrapment rate were used to evaluate the quality of the microspheres.
通过对微球粒径大小、粒径分布、表面形态、流动性、电性、浸水膨胀率、含量测定等项目的考察,检测微球的性能。
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