• In 2007 a group of researchers discovered that the fusion of two normally independent genes, EML4 and ALK, into one aberrant gene seems to drive the formation of tumours.

    2007年一个研究小组发现,两种普通基因(EML4和ALK)和一个异常化基因的融合能形成肿瘤。

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  • Objective:To study on relationship between of BCR/ABL fusion gene expression and TCM syndrome classification in the patient of chronic myelogenous leukemia(CML).

    目的:探讨慢性粒细胞白血病(CML)患者BCR/ABL融合基因表达与中医辨证分型的关系。

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  • After that, introducing weight gene, syncretized PID and fuzzy control's outputs by adding weight. At last, the result of fusion was output to object controlled.

    之后引入加权因子,采用加权的方法将PID和模糊控制各自的输出进行融合,将融合的结果最后输出到被控对象上。

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  • Conclusion The GRA7 gene may be expressed as a GST fusion protein in E. coli.

    结论GRA7基因在大肠埃希菌中以gst融合蛋白的形式得到表达。

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  • Objective: To clone and express the gene of human enterokinase light chain which would be used in the cleavage and purification of fusion proteins.

    研究目的:克隆表达人肠激酶轻链编码基因,以期应用于融合蛋白的切割与纯化。

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  • The specific chromosome and fusion gene are regarded as marker of leukemia, and helpful in leukemia diagnosis, evaluating prognosis, monitoring of treatment and minima residual leukemia.

    特定的染色体和融合基因可作为白血病的标志物,对白血病的诊断、预后估计、监测治疗和微小残留白血病等方面具有一定的价值。

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  • Results: The CAT gene was cloned correctly and it's fusion protein was expressed in E.

    结果:成功克隆了CAT的基因片段,并在大肠杆菌中得到其融合蛋白的表达。

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  • Conclusion 2cvn fusion gene was successfully constructed and highly expressed.

    结论已成功构建了2cvn融合基因,并获得高效表达。

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  • The most commonly used gene delivery methods include: physical method, chemical methods, fusion method and gene gun etc.

    目前基因转运方法有许多种,其中包括物理方法、化学方法,融合法,基因枪等。

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  • Methods Based on the usefulness of gene fusion analysis for transcriptional analysis, two kinds of plasmids and integrant mutant strains were developed for the systemic study of PQS.

    方法基于基因融合分析在转录研究中的实用性,构建了两种PQS相关对照质粒和整合突变株。

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  • The secretion expression vector of fusion gene in E. coli has constructed by fussing the proinsulin gene to the gene of staphylococcal protein a.

    将胰岛素原基因融合到金色葡萄球菌蛋白a的基因上,构建成大肠杆菌中基因融合的外分泌表达载体。

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  • Gene markers which are used to detect minimal residual disease(MRD)include fusion genes(FG), aberrant genes and some genes with high expression in leukemia disease.

    残留白血病检测的基因标志可大致分为融合基因、变异基因和一些白血病中表达增高的基因。

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  • The application of the techniques of large_scale cell culture, somatic cell fusion and gene transformation will greatly change the traditional mode of production and breeding of sweet potato.

    细胞大规模培养、体细胞融合、基因转导等技术的研究和应用,可望从根本上改变甘薯传统的生产和育种模式。

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  • Objective To construct recombinant plasmid with human atrial natriuretic peptide (ANP) gene in fusion form for stable and high level expression of genetic engineering product ANP in E. coli system.

    目的构建以融合蛋白形式在大肠杆菌中高效表达心钠素的重组质粒,稳定高效地获得基因工程产品心钠素。

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  • The construction and application of fusion gene of Farnesyl Pyrophosphate synthase carrying plastid transit peptide belongs to plant genetic engineering field.

    携带质体转运肽的法呢基焦磷酸合成酶融合基因的构建及应用,属于植物基因工程领域。

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  • The tyrosine kinases expressed by BCR-ABL fusion gene can cause cell proliferation, adhesion and survival natural change, several kinds of tumors can be caused by it.

    BCR -ABL融合基因表达出的酪氨酸激酶能引起细胞增殖、黏附和生存性质的改变,导致多种肿瘤的产生。

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  • The purified fusion protein was used as antigen to immunize rabbit for further gene function study.

    该基因的表达成功,为其功能的进一步深入研究奠定了基础。

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  • Objective: To express gastric cancer related gene GCRG213 using thioredoxin fusion expression system.

    目的:利用硫氧还蛋白融合表达系统表达胃癌相关基因gcrg2 13。

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  • Conclusion: the target gene and its fusion protein was successfully expressed, which provide a base for the further research.

    结论:成功克隆葡糖基转移酶CAT基因并获得其融合蛋白的表达,为后续研究奠定了基础。

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  • Using gene fusion technology, polypeptide fusion tags can be engineered into target proteins at the genetic level.

    多肽融合标签能够赋予目标蛋白新的特性,便于目标蛋白的定位、追踪、纯化以及结构和相互作用研究。

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  • Objective: to clone the gene of fructose binding protein BL0033 from Bifidobacterium longum NCC2705, and express and purify fusion protein GST-BL0033 in e.

    目的:克隆长双歧杆菌ncc 2705株果糖结合蛋白bl 0033的基因,利用大肠杆菌表达GST -BL 0033融合蛋白并纯化。

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  • CONCLUSION the fusion protein of the cloned kininogenase gene was highly expressed in E. coli and could be used for the development of its biological products.

    结论成功克隆人胰腺组织激肽原酶基因,并高效表达融合蛋白,为进一步开发基因工程药物打下基础。

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  • Aim: To express the whole length fusion protein of human IRGMa and prepare high quality rabbit anti-human immune-related gene guanosine triphosphate (IRGM) polyclonal antibody.

    目的:表达人免疫相关鸟苷三磷酸酶基因(IRGM) a全长融合蛋白,制备高质量的兔抗人IRGM多克隆抗体。

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  • Conclusion KDR promoter may regulate the CDglyTK fusion gene system to selectively kill the KDR-expressing SCG7901 cells and to induce the cell apoptosis.

    结论KD R启动子可以调控融合基因体系选择性地杀伤人胃癌scg7901细胞,并且该体系可以诱导胃癌细胞凋亡。

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  • This study was aimed to explore the relationship of 6; 9 chromosome translocation with DEK-CAN fusion gene expression in patients with acute myeloid leukemia (AML) and its clinical significance.

    本研究旨在探讨急性髓系白血病(aml)患者6;9染色体易位与DEK - CAN融合基因表达之间的关系及临床意义。

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  • Objective to detect SYT-SSX fusion gene transcripts in fresh-frozen synovial sarcoma specimens and analyze the correlation between histological phenotypes and SYT-SSX subtypes.

    目的检测滑膜肉瘤新鲜冰冻标本中的SYT -SSX融合基因,分析融合基因亚型与病理表型之间的关系。

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  • Objective: To study the influence of tetracycline-controlled system on expression of the DT390-VEGF165 fusion gene in human gastric carcinoma cell.

    目的:研究四环素调控系统对DT390-VEGF165融合基因在人胃癌细胞中表达的影响。

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  • Objective To study the frequency and clinical significance of transloation, ets, leukemia-acute myeloblasticleukemia1 (TEL-AML1) fusion gene in children with acute lymphoblastic leukemia (ALL).

    目的研究TEL-AML1融合基因在儿童急性淋巴细胞白血病(ALL)的发生率及其临床意义。

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  • Objective: to detect the expression of the fusion epitopes gene of foot-and-mouth disease virus (FMDV) in vitro.

    目的:在体外检测口蹄疫病毒融合表位基因的表达。

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  • The principles, operation and applications of site-directed mutagenesis, gene fusion technology, and post-translational modification methods were introduced emphatically.

    着重阐述了基因定点突变技术、基因融合技术和翻译修饰技术等新兴定点固定化技术的原理、特点和操作。

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