The absolute bioavailability of HCPT after aerosol inhalation was 7. 38% .
雾化吸入给药后的绝对生物利用度为7.38％。
The tissue distribution of HCPT after aerosol inhalation or iv administration was compared.
比较雾化吸入和静脉注射给药后的组织分布特点与血药浓度。
To observe the efficacy and toxicity of combination chemotherapy with HCPT/CF/5Fu in advanced colorectal cancer.
目的观察应用草酸铂联合氟尿嘧啶、甲酰四氢叶酸治疗晚期大肠癌的客观疗效及不良反应。
Objective: to prepare 10-hydroxycamptothecin-semisolid lipid nanoparticles (HCPT-SSLN) and investigate its stability.
目的：制备10 -羟基喜树碱的半固体脂质纳米粒(HCPT -SSLN)并考察其稳定性。
AIM: to study the relationship between the lactone forms of 10-hydroxycamptothecin (HCPT) and their antitumor activities.
目的：研究10 -羟基喜树碱(HCPT)的内酯环形式与抗癌活性之间的关系。
The combination regimen with HCPT is safe and effective for advanced colorectal cancer, it's worthy of further clinical trail.
结论HCPT联合方案治疗晚期大肠癌安全有效，值得临床进一步观察研究。
Objective:To investigate drug-resistance mechanism of the camptothecin(HCPT)-resistant stomach cancer cell line SGC-7901/HCPT.
目的：探讨人胃癌耐羟基喜树碱细胞株即SGC-7901/HCPT的耐药机制。
Objective: to observe the response and toxicity of combination with low-dose HCPT and low-dose FLP in patients with advanced digestive carcinoma.
目的：观察低剂量羟基喜树碱(HCPT)联合低剂量flp方案治疗晚期消化系肿瘤的疗效和毒副作用。
RESULTS The two evaluating indices of the CS-Cl-coated HCPT nanoliposomes were both significantly higher than those of the other four groups(P<0.05).
结果HCPT包衣纳米脂质体给药组的瘤重抑制率及肿瘤坏死范围均显著高于其他几种制剂给药组（P<0.05）。
Objective To evaluate the effectiveness and safety of 10-HCPT combined with lipiodol in TACE(transcatheter arterial chemoembolization) for liver metastases.
目的探讨对肝转移瘤以拓僖联合超液化碘油进行化疗栓塞（TACE）治疗的安全性与有效性。
The diameter of L-HCPT was mensurated by laser particle analyzer, and morphological characteristic of L-HCPT was observed by transmission electron microscope.
脂质体的稳定性研究包括采用激光粒度仪检测L-HCPT的粒径大小及多分散指数，用透射电镜观察脂质体的形态。
Conclusion: MEBO use of HCPT in anorectal outpatient anorectal surgery therapy for wound recovery, the clinical results are satisfactory, practical and worthy of promotion.
结论：MEBO在肛肠科使用HCPT疗法进行的门诊肛肠手术创面恢复中，临床效果理想、实用性强、值得推广。
It could induce formation of cellular chromatid breaks and increase the frequency of SCE. The effect of HCPT on SCE was found to parallel to the inhibition of colony formation.
它能引起细胞染色单体断裂，增加sce的频率，其SCE频率的出现与克隆形成能力的抑制呈平行相关。
Conclusion: The results suggested that aerosol delivery of HCPT demonstrated powerful antitumor activity and was useful for melanoma lung metastasis by aerosol delivery treatment.
结论：雾化吸入HCPT给药对于黑色素瘤肺转移癌症的治疗效果明显，具有一定的应用前景和深入研究的潜力。
Objective: In order to offer evidence for the clinical application of HM(harmine), toxicity of HM and HCPT(hydroxycamptothecin) against the rat normal liver cell (BRL) was compared.
目的：通过去氢骆驼蓬碱 （HM）微球与羟基喜树碱 （HCPT）注射液对大鼠正常肝细胞 （BRL ）的毒性作用的比较研究 ，为HM的临床应用提供佐证。
Conclusion: The HCPT-SSLN has high entrapment efficiency and drug loading, uniform particle size, good stability, which initially indicates that HCPT is fit for being incorporated into SSLN.
结论：本实验制备的HCPT - SSLN包封率和载药量较高，粒径分布均匀，稳定性良好。初步表明HCPT适合进行SSLN包裹。
SEP has no significant difference before and after administration. The count of fibroblasts and the area of epidural scar in HCPT and MMC group was obviously less than that in control group.
用药前后各组SEP检测无显著性差异，HCPT组和MMC组成纤维细胞计数和硬膜外瘢痕面积均较对照组明显降低。
SEP has no significant difference before and after administration. The count of fibroblasts and the area of epidural scar in HCPT and MMC group was obviously less than that in control group.
用药前后各组SEP检测无显著性差异，HCPT组和MMC组成纤维细胞计数和硬膜外瘢痕面积均较对照组明显降低。
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