JNK signaling transduction pathway plays a vivtal role in the neuronal apoptosis.
JNK信号转导途径参与神经元凋亡。
Mitochondra play a key role in the process of cerebral ischemic neuronal apoptosis.
线粒体在脑缺血神经元凋亡的发生过程中起着关键作用。
Thus, cerebral NADPH oxidase activation preceded cerebral inflammation and neuronal apoptosis.
因此脑nadph氧化酶的活化早于脑部炎症和神经元的凋亡。
Objective to observe the effect of neuronal apoptosis after seizures of rats induced by kindling.
目的观察点燃大鼠痫性发作对神经元凋亡的影响。
Background and objective: Many genes modulate the neuronal apoptosis following ischemia brain damage.
背景与目的脑缺血损伤后细胞凋亡受诸多基因调控。
Research indicated that the pathogenesis of AD is a series of cascades in brain inducing neuronal damage and neuronal apoptosis.
研究表明,其发病机理是由于一系列级联反应引起的神经元损伤和神经细胞凋亡。
Conclusion the lipid peroxidation after sciatic never injury caused by firearm is one of the important factors for neuronal apoptosis.
结论火器性坐骨神经伤后的脂质过氧化反应是神经元凋亡的重要原因之一。
OBJECTIVE: Controversy over the presence of neuronal apoptosis in a-cute brain injuries has not been resolved due to the lack of direct evidence.
目的:急性颅脑损伤是否存在神经元凋亡一直存在争议,主要原因是缺乏人脑损伤的直接资料来证实这一现象。
Conclusion Seizure could result in the neuronal apoptosis in ictal location and distant area. It might relate to the cause of refractory epilepsy.
结论痫性发作可使痫灶局部和远隔痫灶的神经元凋亡,此可能与顽固性癫痫的成因有关。
BACKGROUND: Cerebral ischemia and reperfusion affects not only cellular necrosis at acute stage, but also delayed neuronal apoptosis in central neural system.
背景:脑缺血再灌注对中枢神经系统的影响,除了急性期的细胞坏死,还有迟发性的神经元凋亡。
Valsartan, but not hydralazine, prevented neuronal apoptosis, being associated with the suppression of apoptosis signal-regulating kinase 1 activation by valsartan.
并非肼屈嗪而是缬沙坦能够防止神经与凋亡,他的作用与其抑制细胞凋亡信号调节激酶1的活性有关。
Neurotrophic factors can sustain the function of central cholinergic neurons as well as inhibit the neuronal apoptosis. They can also modulate the synaptic plasticity.
对影响认知的中枢胆碱能神经元的神经营养支持作用、抑制细胞凋亡、调节突触可塑性等可能是它们发挥保护作用的主要机制。
Results After seizures the number of neuronal apoptosis cells (NNACs) in the hippocampus, the amygdala, the cerebral cortex, the thalamus and the cerebellum increased remarkable.
结果发现痫性发作后海马、杏仁核、大脑皮质、丘脑、小脑神经元凋亡明显增多。
Study Design. An analysis of pain behavior and neuronal apoptosis in the dorsal root ganglion (DRG) following crush injury to the L5 nerve root, with or without surgical sympathectomy.
研究设计:研究L5神经根受挤压伤后接受和不接受交感神经切除术时背根神经节(DRG)的疼痛表现和神经细胞的凋亡情况。
Conclusion PKC took place translocation activation during cerebral ischemia reperfusion, PKC promoted the expression of FOS and BCL 2. Their complex role influenced the neuronal apoptosis.
结论缺血再灌注期间PKC发生易位激活,PK C促进了FOS和BCL -2的表达,这几个因素综合作用影响神经细胞凋亡。
AIM: to probe into the dynamic progression of the space time distribution of neuronal apoptosis and necrosis in rats after focal cerebral infarction and compare their space time correlation.
目的:探讨大鼠局灶性脑梗死后神经细胞凋亡与坏死的时间、空间分布的动态演变及二者时空、时效关系的比较。
Methods: The neuronal apoptosis in CA 1 region of hippocampus following ischemia reperfusion was detected using the MG P MY staining method which combined methyl green, pyronine and martius yellow.
方法:应用甲基绿-派洛宁-马休黄组合染色法,检测沙土鼠脑缺血后海马神经元的凋亡。
Impairment of neuronal mitochondria following hypoxia of brain not only result in nerve cell's energy-deprivation and dysfunction, mitochondria also play key roles in apoptosis of neurons.
脑缺氧后神经元线粒体损伤不单使细胞发生能量缺失和功能丧失,还可以介导凋亡调节信号,是缺氧损伤后神经元凋亡的一个中心环节。
Flow cytometry was used to detect the neuronal cell apoptosis.
流式细胞术检测细胞凋亡;
Flow cytometry was used to detect the neuronal cell apoptosis.
流式细胞术检测细胞凋亡;
应用推荐