• The chiral HMPA analogues were prepared in high yield by nucleophilic substitution between the chiral secondary amine and phosphoryl chloride.

    通过磷酰性仲核取代反应高产率地合成了手性HMPA 类似物

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  • Kinetics of the Nucleophilic Substitution of 3-amino-1, 2, 4-triazole with Picryl Chloride.

    氨基- 1,2,4 -三唑亲核取代反应动力学研究。

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  • Quaternarization is an important SN2 nucleophilic substitution reaction; solvent has remarkable effect on it.

    季铵化反应一类重要SN2亲核取代反应溶剂反应的影响很显著

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  • The chiral HMPA analogues 1 and 2 were prepared in high yield by nucleophilic substitution between the chiral secondary amine and phosphoryl chloride.

    以磷酰氯为原料通过核取代反应高产率地合成了手性HMPA类似物。

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  • Moclobelide was synthesized from ethanolamine by nucleophilic substitution and Schotten-Baumann reaction, followed by condensation with an overall yield of 71.2%.

    乙醇胺为起始原料,亲核取代、肖特鲍曼反应缩合反应制得吗氯贝胺,收率可达71.2%。

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  • The effect of process conditions, such as microwave, reactant ratio, catalyst and solvent etc, on the nucleophilic substitution and yield of product were investigated.

    考察微波技术反应物料催化剂以及溶剂主要条件核取代反应产物收率影响

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  • Aripiprazole in overall yield of 68% was synthesized from 2, 3-dichloroaniline by a three-step nucleophilic substitution reaction in yield of 83%, 91% and 90%, respectively.

    2,3 -二氯苯胺为原料,3步取代反应合成阿立哌唑。3步反应的收率分别为83%,91%90%;收率68%。

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  • Five derivative dyes from the parent dyes were obtained by similar nucleophilic substitution reaction in which five primary amines were employed as the nucleophilic reagent.

    母体染料中位氯原子氨基试剂取代衍生合成了个中位仲七甲川菁染料。

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  • Vicarious nucleophilic substitution (VNS) of hydrogen is a new type of reaction which is different from the usual electrophilic and nucleophilic reactions of the nitro arenes.

    替代取代反应(VNS)硝基芳环反应、亲核反应不同一种反应。

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  • After it was mixed with epoxy resin, transition state was formed first. Then they got on with opening ring reactions according to bimolecular nucleophilic substitution mechanism (SN2).

    环氧树脂混合首先形成过渡状态然后双分子取代(SN2)机理进行反应

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  • At the same time, discuss about the impact factor to nucleophilicity such as the number of attract electron group, ability of attract electron and the nucleophilic substitution reaction part.

    并且核试剂体积效应、溶剂效应亲核性影响,底物上电子基团数目、吸电子能力电性的影响,以及亲核取代反应的发生部位受哪些因素影响进行探讨

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  • The key step of the two routes is the reaction of nucleophilic substitution of aromatic amines and -bromo compounds. Generally the produce rate of this reaction is low and the reaction time is long.

    条路线关键一步反应化合物亲核取代反应,一般步反应,并且需要长的反应时间

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  • METHODS: Electrophilic substitution, reduction, oxidation and nucleophilic addition reaction were used in the synthesis of title compounds.

    方法:通过取代还原氧化加成等反应得到目的化合物

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  • Nucleophilic Aromatic Substitution. Strategies in the Synthesis of Multisubstituted Benzene Derivatives.

    亲核性芳香取代多取代苯衍生物合成策略

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  • Nucleophilic Aromatic Substitution. Strategies in the Synthesis of Multisubstituted Benzene Derivatives.

    亲核性芳香取代多取代苯衍生物合成策略

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