Not surprisingly, the rats put on weight and fat, and developed insulin resistance and glucose intolerance—basically, type 2 diabetes, the scientists reported last month in Nature.
Previous studies have associated large waistlines with heart disease, inflammatory illness, insulin resistance, high blood cholesterol and type 2 diabetes.
3
吡格列酮是一种噻唑烷二酮类药物，可以改善胰岛素敏感性并且改善2型糖尿病的糖脂代谢。
Pioglitazone is a thiazolidinedione that ameliorates insulin resistance and improves glucose and lipid metabolism in type 2 diabetes mellitus.
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