Conclusions: Liuwei Dihuang Pill, Xiaoyao Pill with Shengmai Powder have good therapeutic effects on peri-menopause syndrome, and have no side effects.

Objective: To observe the pharmacological actions of Six Ingredient Rehmannia Pill on animal.

Under the guide of the 1CM kidney-brain related theory, this article explored the effect and some mechanism of liuwei dihuang wan(LW)in curing cerebral ischemia .