Leptin is a trigger for puberty onset in rodents, as a metabolism signals to link reproductive function to the nutritional status, and has a similar effect in childhood growth and development.

Endocrine disrupting chemicals (EDCs) are a group of compounds, which can affect human and animal reproduction and development.

Studies the sheep like-ES cells in vitro, not only as an model of mammalian development in vitro, but also can be used to treat and reproduction, a bright future at prospect of application.