In this study, the immunoreactivity of structural protein VP1 of foot-and-mouth disease virus (FMDV) type o with sera from swine vaccinated against FMDV was analyzed.
Objective to developed a recombinant protein vaccine with epitopes on VP1 protein for prevention of foot-and-mouth disease virus (FMDV) spreading by inactive-FMD vaccine.
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能与口蹄疫病毒感染血清发生特异性反应,而不能与疫苗免疫动物血清发生反应;
The purified protein could specificially react with FMDV infection antibodies in Western blotting assay, but no reaction with the immune antibodies induced with vaccine.