endometrial hyperplasia
Endometrial hyperplasias, which occur in the premenopausal age and are often induced by anovulatory cycles, are kept under control by progestin therapy.
子宫内膜增生具有一定的癌变倾向,故被列为癌前病变。但根据长期观察,绝大数子宫内膜增生是一种可逆性病变,或保持一种持续性良性状态。仅少数病例在较长的时间间隔以后可能发展为癌。根据腺体结构形态改变和有无腺上皮细胞异型性分为3型:①单纯增生:由于无孕酮拮抗的雌激素长期刺激所致的子宫内膜生理性反应。间质与腺体同时增生而无腺体拥挤,腺上皮的形态无异型性。②复合增生:病变区腺体拥挤,间质明显减少,无腺上皮细胞的异型性。③不典型增生:腺上皮有异型性,属于子宫内膜的上皮内肿瘤,按病变的程度,分为轻、中、重三度。