Protect yourself: If you're over age 65, you're more vulnerable to side effects from diphenhydramine, an anticholinergic used in many over-the-counter sleep AIDS and allergy drugs.

These medications are widely used but their anticholinergic and sedative properties may not be well tolerated by patients.

It was found suggest that age, gender, anticholinergic drugs, treatment duration and current dosage as the risk factors have significant effects on the existence of TES at 0.05 or 0.01 level.