A month removed from his first Senate election, Biden's wife and 13-month-old daughter died in a car accident, and Biden was sworn into the Senate at their bedside.

This was after watching Obama's daughter Sasha and Biden's granddaughter Maisy play in a basketball game. The Obama-Biden friendship knows no generational bounds.

Just weeks after winning the Senate seat in 1972, Biden's wife, Neilia, and 1-year-old daughter, Naomi, were killed in a car accident.