Conclusion The expression increase of MLCK in bronchial smooth muscle may be correlated with asthmatic pathogenesis.

NO can lower the pressure of pulmonary artery and relieve the bronchospasm through dilating the smooth muscle of blood vessel and relaxing the smooth muscle of bronchus.

CONCLUSION: Over expression of TERT in pulmonary vascular smooth muscle cells and bronchial smooth muscle cells is related to MCT-induced PH.