Specifically affected were genes involved in chromatin remodeling.
2
是进化上高度保守的SWI/SNF染色质重塑复合物的成员之一。
BRG1(brahma-related gene 1)is a component of the evolutionarily conserved SWI/SNF chromatin-remodeling complex.
3
表观遗传学涉及的机制主要包括DNA甲基化和组蛋白修饰及染色质重塑。
Epigenetic mechanisms, including DNA methylation, histone modification and chromatin remodeling, have been demonstrated to be involved in the development of SLE.