Conclusion Diabetic nephropathy and autonomic neuropathy can affect renin, angiotensin and aldosterone system, and is easy to cause hypoaldosteronemia.

It includes specific myocardium pathological of diabetes, heart capillary pathological changes, trunk blood vessel pathological changes, heart plant neuropathy related to diabetes changes.

The non-linear indices among normal, single-vessel, multi-vessel coronary artery disease patients, and diabetic patients showed markedly difference.