CONCLUSIONS Methylene blue photochemical methods can be used to inactivate the main transfusion infected viruses, and the normal activities of plasma still keep at very high level.

In one method they were prepared from whole viruses or bacteria that had been killed to prevent infection.

Overall, prions may not be highly resistant to reprocessing methods, depending on the process used, and efficacy against prions does not imply that other micro-organisms have been inactivated.