Less common clinic features including uveitis, cutaneous nodules or pustules, synovitis, meningoencephalitis, large vessel arteritis, phlebitis, intestinal ulceration.

Conclusions: Depending on the analysis and treatment of this case, the nodules on shanks might originate from myxedema caused by hypothyroidism and can be cured by eliminating the origin of a disease.

Advanced gout. Untreated gout may cause deposit of urate crystals to form under the skin in nodules called tophi (TOE-fi).