Much more work will need to be done to untangle how other environmental pollutants -- like the plastic additive bisphenol A -- may also contribute to America's ballooning diabetes problem.

In recent years, diabetes whose incidence is keeping increased has become a serious impact on human mental and physical health and become a key public health issues and major diseases.

The diabetic foot is one of the common severe complication of diabetes, its high incidence and mutilation rate have been a public health problem.