Objective: to establish the rabbit model of acute lung injury (ALI) by intratracheal instillation of Escherichia coli, and to study the pathogenesis of bacteria-induced ALI.

Enterococcus faecalis (E. faecalis) is most frequent isolated from teeth with failed endodontic treatment. Biofilm-formation is one of the most important pathogenic mechanisms in post-treatment teeth.

The study of resistance mechanism induced by fungi and bacteria lagged behind that of virus.